{"id":"W2582670998","doi":"10.1182/blood-2016-09-738005","title":"S100A9 induces differentiation of acute myeloid leukemia cells through TLR4","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital de l'Enfant-Jésus; Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Myeloid leukemia; Medicine; Cancer research; Leukemia; Myeloid; Myeloid cells; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087909,0.0003778262,0.0002926931,0.0003452147,0.0001465084,0.000209346,0.0001388934,0.0002064733,0.001906077],"category_scores_gemma":[0.00009090697,0.0001435076,0.0003933151,0.0001976539,0.0001585987,0.0001294351,0.0002866827,0.0007207477,0.0008107508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000262931,"about_ca_system_score_gemma":0.0001977832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004727828,"about_ca_topic_score_gemma":0.0007220202,"domain_scores_codex":[0.9997972,0.0000374183,0.00002492489,0.00002718091,0.00004796538,0.00006541976],"domain_scores_gemma":[0.9999295,0.00001135203,0.00001765143,0.00000935609,0.000009036456,0.00002303523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002974134,0.0001059952,0.0003355466,0.00006154446,0.000007023709,0.00006025706,0.0000187982,0.00007394617,0.9967719,0.00007661187,0.0001110921,0.002079889],"study_design_scores_gemma":[0.0001408404,0.001086224,0.01522867,0.00001456035,0.00003114979,0.0003263435,0.00007844316,0.002831112,0.9737307,0.0001571615,0.006367925,0.000006973856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933997,0.001091672,0.001971339,0.0001641983,0.00003657089,0.0000725538,0.0005201883,0.0001265811,0.002617173],"genre_scores_gemma":[0.9923934,0.0007374682,0.002051903,0.0001392293,0.00001485704,0.00009706172,0.0009894556,0.00001348901,0.003563171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001906077,"threshold_uncertainty_score":0.006376445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01269789145927907,"score_gpt":0.2495983856824797,"score_spread":0.2369004942232006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}