{"id":"W2582746542","doi":"10.1016/j.neo.2016.12.007","title":"PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail","year":2017,"lang":"en","type":"article","venue":"Neoplasia","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Snail; Biology; Cancer research; Transcription factor; Transcriptome; Cancer; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001048924,0.0001944496,0.0001616087,0.0001804176,0.0001424126,0.0002578417,0.00008991362,0.0001291673,0.001714652],"category_scores_gemma":[0.000121927,0.0001003942,0.0001579579,0.0001247494,0.0002281575,0.0001407472,0.0002263869,0.0004898076,0.0003177753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001812566,"about_ca_system_score_gemma":0.0001652072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003926509,"about_ca_topic_score_gemma":0.000654946,"domain_scores_codex":[0.9999176,0.00001160271,0.00000694457,0.0000193438,0.00002238748,0.00002213518],"domain_scores_gemma":[0.9999321,0.00001022504,0.00002052405,0.000008184943,0.000008590591,0.00002042503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003351598,0.00004585679,0.003102826,0.0001078275,0.000009989444,0.000139022,0.00003045994,0.0001965311,0.9920649,0.0001884244,0.0002064295,0.003572663],"study_design_scores_gemma":[0.00006241223,0.0003596594,0.04500965,0.00001771574,0.00003712317,0.0006837801,0.0001197204,0.004457477,0.94174,0.0001495556,0.007352286,0.00001057831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936277,0.001531775,0.002430639,0.0001419067,0.00001614287,0.00001868827,0.0004770608,0.0001406815,0.001615494],"genre_scores_gemma":[0.9970227,0.0004002987,0.0004827697,0.00002893675,0.000002295015,0.00001578972,0.0003547375,0.000009518859,0.001683148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001714652,"threshold_uncertainty_score":0.005736053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02077774183611627,"score_gpt":0.318758998517532,"score_spread":0.2979812566814157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}