{"id":"W2582746542","doi":"10.1016/j.neo.2016.12.007","title":"PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail","year":2017,"lang":"en","type":"article","venue":"Neoplasia","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Snail; Biology; Cancer research; Transcription factor; Transcriptome; Cancer; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001895544,0.0001248281,0.0002296103,0.00001522202,0.0002654977,0.00003233801,0.0001545567,0.00006749167,0.0005680181],"category_scores_gemma":[0.00001954974,0.00007973819,0.0001128829,0.00003202325,0.0001602548,0.0001198425,0.00003332102,0.0001444567,0.000004660835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006459258,"about_ca_system_score_gemma":0.0001805895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006886369,"about_ca_topic_score_gemma":0.0002315717,"domain_scores_codex":[0.9991053,0.00003009991,0.000142175,0.000204156,0.0003103451,0.0002079771],"domain_scores_gemma":[0.9992611,0.00003139151,0.0001875961,0.0003722957,0.00005917082,0.00008843642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009722994,0.0005500094,0.03556635,0.0003652288,0.0001332461,0.0000298777,0.001404318,0.000004182976,0.6703537,0.000257851,0.006797325,0.2835657],"study_design_scores_gemma":[0.003266613,0.0005095478,0.1404815,0.000322494,0.0003040254,0.00003359389,0.0002065642,0.000213105,0.8090341,0.0000730077,0.04536714,0.0001883002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879482,0.002251977,0.0001136089,0.002056566,0.000289517,0.0004143229,0.00008620817,0.00002055083,0.006819072],"genre_scores_gemma":[0.9974329,0.0002766571,0.0002963903,0.00008596919,0.0001811824,0.00005774617,0.00001011697,0.00001756651,0.00164141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2833773,"threshold_uncertainty_score":0.62194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02077774183611627,"score_gpt":0.318758998517532,"score_spread":0.2979812566814157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}