{"id":"W2583082560","doi":"10.1530/erc-16-0496","title":"Pituitary acromegaly: not one disease","year":2017,"lang":"en","type":"letter","venue":"Endocrine Related Cancer","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Acromegaly; Risk stratification; Pituitary tumors; Epigenetics; Pituitary adenoma; Disease; Medicine; Bioinformatics; Broad spectrum; Adenoma; Pathology; Neuroscience; Biology; Internal medicine; Genetics; Growth hormone; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007746034,0.0005386216,0.00117673,0.0005615363,0.001426094,0.001474466,0.0007504448,0.007960948,0.002621683],"category_scores_gemma":[0.007301192,0.0002801565,0.0005161434,0.0004684835,0.002332002,0.002609775,0.001059832,0.01205687,0.002373985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002206288,"about_ca_system_score_gemma":0.001372519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001462832,"about_ca_topic_score_gemma":0.003000414,"domain_scores_codex":[0.9992611,0.0002348844,0.0000783136,0.000104321,0.0002059384,0.0001154873],"domain_scores_gemma":[0.9975248,0.001242753,0.0002494486,0.0001441153,0.0003625788,0.0004763262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002641827,0.00009255121,0.01091539,0.0008626984,0.0001323055,0.2569805,0.000613786,0.0004666391,0.002226686,0.02163629,0.576403,0.1294059],"study_design_scores_gemma":[0.0001554311,0.0001274283,0.004203847,0.001070007,0.00007672413,0.5722835,0.0008115477,0.0009197186,0.0005914593,0.04037289,0.3792957,0.00009184104],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.008715733,0.05088212,0.0007701946,0.9077427,0.01782103,0.00001877926,0.00008879687,0.0001049346,0.01385572],"genre_scores_gemma":[0.1945442,0.08607911,0.002028784,0.5159394,0.1898318,0.00005922927,0.0001529465,0.00008391845,0.01128067],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.007960948,"threshold_uncertainty_score":0.01600778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02703821333650549,"score_gpt":0.3045985027313428,"score_spread":0.2775602893948373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}