{"id":"W2583406819","doi":"10.1111/tan.12966","title":"Typing and copy number determination for <scp>HLA‐DRB3</scp>, ‐<scp>DRB4</scp> and ‐<scp>DRB5</scp> from next‐generation sequencing data","year":2017,"lang":"en","type":"article","venue":"HLA","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canada's Michael Smith Genome Sciences Centre","keywords":"Typing; Human leukocyte antigen; Biology; Population; Genetics; Haplotype; Computational biology; Polymerase chain reaction; DNA sequencing; Allele; Gene; Antigen; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0006305614,0.0004811461,0.0006172259,0.0001351628,0.001630318,0.0004157583,0.0008189159,0.0008504385,0.00003865324],"category_scores_gemma":[0.002166563,0.0004721557,0.00009175502,0.0000780468,0.0006165209,0.001050177,0.0007435021,0.0005159258,0.0003163145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000811578,"about_ca_system_score_gemma":0.0001398407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006736339,"about_ca_topic_score_gemma":0.0004369689,"domain_scores_codex":[0.9971761,0.0002566377,0.0005789517,0.00110401,0.00007443054,0.000809914],"domain_scores_gemma":[0.9961897,0.001635024,0.0005949531,0.001315363,0.0001816199,0.0000833549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009295788,0.00006665132,0.005655011,0.00005262912,0.0001709026,0.00001210125,0.001349133,0.00000175481,0.9592111,0.0003981768,0.02057383,0.01249944],"study_design_scores_gemma":[0.004655268,0.0003180048,0.006333102,0.0001648775,0.0004101496,0.0003286769,0.002433242,0.002403903,0.6740744,0.001972605,0.3067091,0.0001967596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856067,0.00576266,0.002733938,0.0001238543,0.001883361,0.0006208984,0.0003372145,0.0001385462,0.002792792],"genre_scores_gemma":[0.9832644,0.001354995,0.002010493,0.0003340337,0.0004765048,0.00007599737,0.002338322,0.00007617939,0.01006904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2861352,"threshold_uncertainty_score":0.999773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07699803336984364,"score_gpt":0.287782332919056,"score_spread":0.2107842995492124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}