{"id":"W2583406819","doi":"10.1111/tan.12966","title":"Typing and copy number determination for <scp>HLA‐DRB3</scp>, ‐<scp>DRB4</scp> and ‐<scp>DRB5</scp> from next‐generation sequencing data","year":2017,"lang":"en","type":"article","venue":"HLA","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canada's Michael Smith Genome Sciences Centre","keywords":"Typing; Human leukocyte antigen; Biology; Population; Genetics; Haplotype; Computational biology; Polymerase chain reaction; DNA sequencing; Allele; Gene; Antigen; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001393697,0.000434,0.0002925497,0.001296719,0.0003666825,0.0006292813,0.0005813864,0.0004439881,0.00127861],"category_scores_gemma":[0.003869637,0.0002145096,0.000545174,0.0009982992,0.0002836026,0.0003563015,0.0003844513,0.0004111618,0.0006432207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003869271,"about_ca_system_score_gemma":0.0002854692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001928511,"about_ca_topic_score_gemma":0.002620535,"domain_scores_codex":[0.99892,0.0002214312,0.000100929,0.0003702147,0.0003181219,0.00006939444],"domain_scores_gemma":[0.9983944,0.0006711742,0.0003243713,0.0002579123,0.0002901103,0.00006193096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005182317,0.0001022682,0.4185789,0.0004348563,0.000389619,0.0007126587,0.0005980779,0.03592361,0.4148118,0.001535658,0.001624868,0.1247695],"study_design_scores_gemma":[0.00004368485,0.0001704515,0.2328821,0.00008486421,0.0003471506,0.00163334,0.0002400384,0.4005492,0.3543344,0.002671421,0.006921569,0.0001218609],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8518667,0.0003918573,0.1422497,0.0001140148,0.00002794089,0.00006762123,0.002912607,0.0007366875,0.001632936],"genre_scores_gemma":[0.8428991,0.000150897,0.1504888,0.00007194703,0.00001430901,0.00007372819,0.005318775,0.0001140112,0.0008684366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001928511,"threshold_uncertainty_score":0.007370651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07699803336984364,"score_gpt":0.287782332919056,"score_spread":0.2107842995492124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}