{"id":"W2583427555","doi":"10.1016/j.bpj.2016.11.598","title":"Role of Channel Fluctuations in Ion Transport and Selectivity in Bacterial Sodium Channel NavAb","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Chemistry; Permeation; Selectivity; Side chain; Molecular dynamics; Sodium channel; Membrane; Isomerization; Ion channel; Sodium; Biophysics; Computational chemistry; Organic chemistry; Polymer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005495205,0.0001820726,0.0003388518,0.0002077995,0.0004008743,0.0009793427,0.0002760847,0.0003356545,0.0008599013],"category_scores_gemma":[0.00135867,0.0002241499,0.0001667551,0.0001478148,0.0006508777,0.0008543602,0.0004550989,0.0005172786,0.0001329483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005280328,"about_ca_system_score_gemma":0.0002169375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006881344,"about_ca_topic_score_gemma":0.0005253149,"domain_scores_codex":[0.9997938,0.00005550062,0.00001653008,0.0000497436,0.00004292495,0.00004147954],"domain_scores_gemma":[0.9995148,0.0002108151,0.00007834311,0.00004900175,0.0000604728,0.00008639657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006137144,0.00007983878,0.006205848,0.00005196438,0.00002782901,0.000351506,0.0001698633,0.004585897,0.9735706,0.006169172,0.000239654,0.007934045],"study_design_scores_gemma":[0.00008926497,0.0005375656,0.1012574,0.00002546763,0.00007540917,0.001438717,0.0004733937,0.3544749,0.528636,0.01086882,0.001949577,0.0001733787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923224,0.0003363651,0.006336705,0.0002377809,0.0000315425,0.000005945461,0.00004535286,0.0000782398,0.000605651],"genre_scores_gemma":[0.9995732,0.00004042801,0.0002649938,0.00001360187,0.000006395409,0.000001737719,0.00001112977,0.00001111191,0.00007751234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009793427,"threshold_uncertainty_score":0.003831208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01071802291818395,"score_gpt":0.2422237472802365,"score_spread":0.2315057243620526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}