{"id":"W2583428451","doi":"10.1182/blood.v104.11.1969.1969","title":"Generation of a Pre-Leukemic, Transplantable Cell Line from the AML-Associated NUP98-TOP1 Fusion Gene as a New Model To Test Potential Collaborating Genes.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Fusion gene; Haematopoiesis; Cell culture; Molecular biology; Transplantation; Stem cell; Bone marrow; Cancer research; Chromosomal translocation; Progenitor cell; Cell biology; Gene; Immunology; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002681718,0.0004055007,0.0003374157,0.0003472424,0.0002901445,0.0003587144,0.0004328753,0.000457698,0.002693352],"category_scores_gemma":[0.00012614,0.000173634,0.000259307,0.0002764693,0.0002475969,0.0002614475,0.000250595,0.001203088,0.00123812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003364671,"about_ca_system_score_gemma":0.0001676372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007063245,"about_ca_topic_score_gemma":0.001015685,"domain_scores_codex":[0.999759,0.00002521906,0.0000337648,0.00004586213,0.0001078499,0.00002833671],"domain_scores_gemma":[0.9997922,0.0000349587,0.00004082046,0.00004103146,0.00002267464,0.00006848042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004098055,0.00005968257,0.0001023131,0.00001451886,0.000002687595,0.00005414822,0.00001483915,0.00005268555,0.99893,0.0001778523,0.00005933484,0.0004908612],"study_design_scores_gemma":[0.00003322064,0.0003905093,0.002116155,0.000005503848,0.00001725915,0.0004418984,0.00003151052,0.001678676,0.9894744,0.00005962955,0.005746529,0.000004758966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712332,0.000725194,0.01741642,0.0002652785,0.0001314097,0.0005096352,0.005196722,0.0002663838,0.004255817],"genre_scores_gemma":[0.968699,0.0005687072,0.01348773,0.00007725808,0.00002367665,0.0003147249,0.005200552,0.00009060353,0.0115378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002693352,"threshold_uncertainty_score":0.009010196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009710767940772249,"score_gpt":0.2143480067862502,"score_spread":0.204637238845478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}