{"id":"W2584067066","doi":"","title":"Ocular Gene Therapy for Choroideremia: the Alberta Experience","year":2016,"lang":"en","type":"article","venue":"","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Choroideremia; Genetic enhancement; Medicine; Ophthalmology; Gene; Biology; Genetics; Retinal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006754354,0.00008464112,0.00005058073,0.000006834177,0.00007672185,0.0000129428,0.0001788584,0.00005695452,0.00008616374],"category_scores_gemma":[0.0000602778,0.00003795892,0.00006198477,0.00002499943,0.00006045628,0.000002211388,0.00003394576,0.00001208081,0.00001381678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003272098,"about_ca_system_score_gemma":0.00002434448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002829677,"about_ca_topic_score_gemma":0.00005622544,"domain_scores_codex":[0.9994904,0.00001225525,0.00008701145,0.0001937061,0.00005881977,0.0001578328],"domain_scores_gemma":[0.9996692,0.00002393235,0.00002287394,0.0002175903,0.00003662628,0.00002976367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001057645,0.00001704641,0.006454653,0.000001238637,0.00002518667,1.576529e-7,0.00008735278,3.895624e-7,0.9662495,0.0005205357,0.009676828,0.01686136],"study_design_scores_gemma":[0.0005060744,0.00007570903,0.001991988,0.000001788171,0.000001440264,0.000002250058,0.00006254936,0.000001891,0.6131524,0.0002286374,0.3838778,0.00009738185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761927,0.0007446846,0.0136855,0.002529367,0.00009722477,0.0003038178,0.00000169141,0.000007068784,0.006437924],"genre_scores_gemma":[0.9795767,0.0009234977,0.0007866418,0.00125561,0.00009067418,0.0001278616,0.00001240413,0.00001185854,0.01721476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.374201,"threshold_uncertainty_score":0.154792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01004171423334654,"score_gpt":0.2488316961953958,"score_spread":0.2387899819620493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}