{"id":"W2584537058","doi":"10.1016/j.bpj.2016.11.1361","title":"The Isolated Voltage Sensing Domain of the Shaker Potassium Channel forms a Cation Channel","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Advanced Memory and Neural Computing","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Shaker; Chemistry; Ion channel; Membrane potential; Biophysics; Potassium channel; Depolarization; Gating; Ion; Relaxation (psychology); KcsA potassium channel; Coupling (piping); Materials science; Biochemistry; Physics; Vibration","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002049864,0.0001917318,0.0007327397,0.0001644913,0.0004888813,0.0007800839,0.0005971663,0.0006581399,0.001311069],"category_scores_gemma":[0.0004372494,0.0001721699,0.0002980104,0.0001728637,0.0007049147,0.001281421,0.0006416799,0.0007689459,0.0009657633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003027958,"about_ca_system_score_gemma":0.000377623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001724665,"about_ca_topic_score_gemma":0.0002659621,"domain_scores_codex":[0.9998405,0.00002007239,0.00001152234,0.00004576424,0.00004792521,0.00003419307],"domain_scores_gemma":[0.9996156,0.00007885053,0.0000537573,0.00005249779,0.00005305764,0.0001463001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003625983,0.00006588444,0.0008508386,0.0001064823,0.0000317027,0.0002245758,0.00009516956,0.0003247588,0.9919164,0.002151174,0.0002478335,0.003622758],"study_design_scores_gemma":[0.0001802051,0.0006173584,0.009544769,0.00002897782,0.00009668609,0.001950316,0.0004126274,0.0166196,0.9599035,0.00457908,0.00599028,0.00007663365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910353,0.0006610603,0.00625922,0.0001888533,0.00009336729,0.00001479293,0.00006133557,0.0001686808,0.001517485],"genre_scores_gemma":[0.9961172,0.000250068,0.001935519,0.0001195739,0.00002378314,0.000009174467,0.000133068,0.00003023637,0.0013814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001311069,"threshold_uncertainty_score":0.004385948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01432725864761412,"score_gpt":0.2367723713666992,"score_spread":0.222445112719085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}