{"id":"W2584571774","doi":"10.1016/j.bpj.2016.11.826","title":"In Vitro Binding of 6S RNA Mango to RNA Polymerase by Two Photon Fluorescence Cross Correlation Spectroscopy","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"RNA; RNA polymerase; Molecular biology; In vitro; Polymerase; RNA-dependent RNA polymerase; Chemistry; Biophysics; RNA polymerase I; RNA polymerase II; Biology; Biochemistry; DNA; Gene expression; Gene; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005471279,0.000425252,0.0005273942,0.0001759609,0.0005749947,0.0006530284,0.0006016375,0.0005317676,0.00136087],"category_scores_gemma":[0.0008782319,0.0004104539,0.0003362819,0.0003263698,0.000450732,0.0003114378,0.0003100995,0.001149941,0.0004191879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008833013,"about_ca_system_score_gemma":0.001063023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007071532,"about_ca_topic_score_gemma":0.00982761,"domain_scores_codex":[0.9995641,0.0001004897,0.00001395957,0.0001282736,0.0001020164,0.0000911185],"domain_scores_gemma":[0.9994472,0.0003222666,0.00005704423,0.00005403915,0.00005231618,0.00006715257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001085445,0.00004878569,0.0001590737,0.00003403524,0.000006403856,0.00003678182,0.00005397283,0.0006398027,0.9977828,0.0002271912,0.00005069219,0.0008519171],"study_design_scores_gemma":[0.000008602951,0.00008193096,0.001158668,0.000004424367,0.000005702941,0.00002020573,0.00002765135,0.008445438,0.9897996,0.00006718159,0.0003654771,0.00001504006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829462,0.0003609288,0.01478003,0.0001058832,0.00003360716,0.00003809781,0.0001401179,0.0001280585,0.001467039],"genre_scores_gemma":[0.9880677,0.0003217736,0.00803211,0.00005780951,0.00001474922,0.00004879804,0.0003708983,0.00004502411,0.003041179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007071532,"threshold_uncertainty_score":0.01406074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009548906344344427,"score_gpt":0.2884917443188421,"score_spread":0.2789428379744977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}