{"id":"W2584787747","doi":"10.1139/bcb-2016-0206","title":"Comparison of the effects of nobiletin and letrozole on the activity and expression of aromatase in the MCF-7 breast cancer cell line","year":2017,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Bioactive Compounds in Plants","field":"Agricultural and Biological Sciences","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"MCF-7; Aromatase; Letrozole; Breast cancer; Nobiletin; Internal medicine; Aromatase inhibitor; Oncology; Cancer; Cancer research; Medicine; Biology; Endocrinology; Human breast; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000135977,0.00007779367,0.0001465821,0.000001668873,0.0001237507,0.000007505189,0.0002381188,0.00009625829,0.00001017665],"category_scores_gemma":[0.0000351416,0.00002091149,0.00002094721,0.00002169065,0.000455038,0.00001324808,0.0001438147,0.0000907003,4.759989e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003259659,"about_ca_system_score_gemma":0.000003632028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003284454,"about_ca_topic_score_gemma":0.00006483647,"domain_scores_codex":[0.9995329,0.0001038181,0.00009516239,0.0001417853,0.00004573816,0.00008053159],"domain_scores_gemma":[0.9991438,0.0004924051,0.0002205154,0.0001137098,0.00001375181,0.00001576186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007295975,0.0001155326,0.07471264,0.00006909583,0.000002133365,1.439085e-7,0.0000394394,5.384056e-8,0.9220811,0.000003827608,0.00007708498,0.002826021],"study_design_scores_gemma":[0.0001030144,0.00008575486,0.2653829,0.00005029037,0.000004991873,0.000001159551,0.0001150196,0.000005864488,0.734109,0.00001716241,0.00009419414,0.00003061958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981994,0.0007547553,6.773446e-8,0.0003911184,0.00003288361,0.0001079113,0.0001942534,0.000001137458,0.0003184712],"genre_scores_gemma":[0.9996552,0.0002618385,0.000001878521,0.00002592241,0.00002902356,0.000006351574,0.000005108667,3.297229e-7,0.00001429937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1906703,"threshold_uncertainty_score":0.1676607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01814309169287315,"score_gpt":0.2639692918487563,"score_spread":0.2458262001558832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}