{"id":"W2584870882","doi":"10.1161/circulationaha.116.022907","title":"Gene Expression Profiling for the Identification and Classification of Antibody-Mediated Heart Rejection","year":2017,"lang":"en","type":"article","venue":"Circulation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"","keywords":"Medicine; Heart transplantation; Gene expression profiling; Immunostaining; Lung transplantation; Pathology; Immunology; Antibody; Biopsy; Pathophysiology; Gene expression; Transplantation; Immunohistochemistry; Gene; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000526483,0.0000596873,0.0001169121,0.00005284404,0.0003519247,0.00003846693,0.00004238979,0.00006807343,0.000003327877],"category_scores_gemma":[0.0003663493,0.00004392895,0.00004521704,0.00004145789,0.00005786225,0.0001764985,0.00000555441,0.00004807041,0.000001779925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001698214,"about_ca_system_score_gemma":0.00002365372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001263735,"about_ca_topic_score_gemma":0.00000207907,"domain_scores_codex":[0.9993536,0.00003300956,0.0002578208,0.0001587997,0.0001292702,0.00006744924],"domain_scores_gemma":[0.9990517,0.0001748263,0.0002806353,0.0003108674,0.000157342,0.00002460611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005570193,0.00001095022,0.3232154,0.00008420066,0.00000811791,5.782067e-8,0.00009181864,0.00001382102,0.6735967,0.0002217298,0.00000669124,0.002694806],"study_design_scores_gemma":[0.0005100037,0.00001400668,0.7781488,0.00004863503,0.00007575172,0.000006354438,0.00005165733,0.009860995,0.2109815,0.0002016459,0.00006543421,0.00003524379],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8122702,0.0001323531,0.1857183,0.0009180671,0.0002075767,0.0006745752,0.00001060543,0.00002277097,0.00004562987],"genre_scores_gemma":[0.9900514,0.00007933215,0.009421458,0.00002191783,0.0001110348,0.00003992422,0.0002363763,0.000009607724,0.00002889827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4626153,"threshold_uncertainty_score":0.2706756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08154976609988084,"score_gpt":0.3918215356397241,"score_spread":0.3102717695398432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}