{"id":"W2584870882","doi":"10.1161/circulationaha.116.022907","title":"Gene Expression Profiling for the Identification and Classification of Antibody-Mediated Heart Rejection","year":2017,"lang":"en","type":"article","venue":"Circulation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"","keywords":"Medicine; Heart transplantation; Gene expression profiling; Immunostaining; Lung transplantation; Pathology; Immunology; Antibody; Biopsy; Pathophysiology; Gene expression; Transplantation; Immunohistochemistry; Gene; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007303127,0.000236075,0.0003403067,0.00171043,0.0001738635,0.0004738042,0.0001968531,0.0003394236,0.0008504588],"category_scores_gemma":[0.0006696903,0.00009207665,0.0002488066,0.0009905659,0.0002414956,0.0001852582,0.0002067226,0.0002958801,0.0003067325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003556123,"about_ca_system_score_gemma":0.0002149773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008356248,"about_ca_topic_score_gemma":0.001317824,"domain_scores_codex":[0.9995362,0.00009781749,0.00003192053,0.000139352,0.0001219117,0.00007281487],"domain_scores_gemma":[0.999467,0.0001508302,0.0001769688,0.0000379247,0.0001167014,0.00005069932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009284322,0.0001631044,0.6526201,0.000170873,0.0001405743,0.0001401727,0.0001689927,0.0005676876,0.3020372,0.0001312595,0.0005296216,0.04240201],"study_design_scores_gemma":[0.00001353569,0.0003728427,0.9566651,0.00002450972,0.00009497045,0.0006084595,0.0001748461,0.003920396,0.03616511,0.0001580559,0.001789538,0.00001251398],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894364,0.002709861,0.004967568,0.0001087118,0.00001992632,0.00005896491,0.001621309,0.000066429,0.001010775],"genre_scores_gemma":[0.9904804,0.0007115398,0.006633846,0.00008435054,0.00002562074,0.00007583824,0.001527374,0.00001119506,0.0004498968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00171043,"threshold_uncertainty_score":0.003862262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08154976609988084,"score_gpt":0.3918215356397241,"score_spread":0.3102717695398432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}