{"id":"W2585019257","doi":"10.1182/blood.v112.11.703.703","title":"The POZ/BTB Domain Transcription Factor Miz-1 (Zbtb17) Is Required during Early B Cell Development for the Survival of B-Cell Progenitors and Is Essential for the Formation of Mature Follicular B Cells","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Biology; B cell; CD19; PAX5; Transcription factor; Lymphopoiesis; Cell biology; Progenitor cell; Bone marrow; Haematopoiesis; Stromal cell; Molecular biology; Immunology; Stem cell; Antibody; Cancer research; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009287409,0.0003239543,0.0002158115,0.0002942367,0.0002397022,0.0003960253,0.0002916152,0.0002936678,0.001612419],"category_scores_gemma":[0.0001018083,0.000252584,0.0001858676,0.0001482487,0.0003561341,0.0002155703,0.0003444541,0.0005892276,0.0009178743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002684765,"about_ca_system_score_gemma":0.0002359094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005041259,"about_ca_topic_score_gemma":0.0005031082,"domain_scores_codex":[0.999821,0.00002269147,0.0000162331,0.00003683759,0.00004975563,0.00005356122],"domain_scores_gemma":[0.9997539,0.00001968277,0.0001264637,0.00001291189,0.00001346362,0.00007355331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000444048,0.000005220021,0.0002433994,0.00002047333,0.000001983556,0.00003395234,0.000006287144,0.00002642235,0.9991664,0.00008589775,0.00001141314,0.0003541259],"study_design_scores_gemma":[0.0000161622,0.0001030798,0.008149173,0.000008570757,0.00001530652,0.0004536485,0.00003587233,0.0004648289,0.9871562,0.00004787986,0.003546146,0.000003226103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919639,0.00184063,0.004482883,0.00007855285,0.00002101575,0.00001568343,0.0008120494,0.0001195496,0.0006657662],"genre_scores_gemma":[0.9934587,0.0007033522,0.002029517,0.00002634493,0.000006603911,0.00002184667,0.001141677,0.00003858552,0.0025733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001612419,"threshold_uncertainty_score":0.005394101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109228180710114,"score_gpt":0.199968692241808,"score_spread":0.1890458741707967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}