{"id":"W2585146168","doi":"10.1182/blood.v120.21.3333.3333","title":"Human and Murine Immune Thrombocytopenia (ITP) Is Associated with a Peripheral Deficiency of CD4- T Regulatory Cells (Tc-regs)","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; St. Michael's Hospital","funders":"","keywords":"FOXP3; IL-2 receptor; CD8; Immunology; Population; Regulatory T cell; Immune system; Flow cytometry; Peripheral tolerance; Peripheral blood mononuclear cell; T cell; Medicine; Immune tolerance; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001677423,0.0004353634,0.0003143858,0.0004988106,0.0001432039,0.0001512888,0.00008480805,0.0002137216,0.001869569],"category_scores_gemma":[0.0001740624,0.0001150832,0.0001860607,0.000327358,0.0002163891,0.0001114703,0.0001777517,0.0003201405,0.0002501531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001112388,"about_ca_system_score_gemma":0.0001002514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002138033,"about_ca_topic_score_gemma":0.0002526312,"domain_scores_codex":[0.9998547,0.00003979309,0.00001365336,0.0000326699,0.00003516782,0.00002398221],"domain_scores_gemma":[0.9998763,0.0000222015,0.00004414103,0.00001778701,0.000007943147,0.00003170243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0064552,0.0008926537,0.08105505,0.0003221273,0.0001630367,0.008016132,0.0003019097,0.0004307924,0.8629286,0.0006323641,0.0009081674,0.03789387],"study_design_scores_gemma":[0.001040172,0.02762528,0.60421,0.0001129052,0.0004122395,0.1319686,0.0002970972,0.001849267,0.2069655,0.0006254043,0.02485363,0.0000398649],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952052,0.00233338,0.0008124788,0.00003191568,0.00001237283,0.00003537504,0.0002389359,0.0000310268,0.001299494],"genre_scores_gemma":[0.9979653,0.0006894363,0.0002884449,0.00002894036,0.00001439327,0.00002093405,0.0003548045,0.00000400865,0.0006336777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001869569,"threshold_uncertainty_score":0.006254315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116340257510698,"score_gpt":0.2376925238848902,"score_spread":0.2265291213097832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}