{"id":"W2585208686","doi":"10.1002/mabi.201600430","title":"Polymeric Delivery of siRNA against Integrin‐β1 (CD29) to Reduce Attachment and Migration of Breast Cancer Cells","year":2017,"lang":"en","type":"article","venue":"Macromolecular Bioscience","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society","keywords":"Integrin; Small interfering RNA; Cancer research; Breast cancer; Cancer cell; Fibronectin; Cell migration; Chemistry; Gene silencing; Cell biology; Cell adhesion; Cancer; Extracellular matrix; Cell; Biology; Medicine; Transfection; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000155222,0.0002495369,0.0001799781,0.0001907791,0.0001077233,0.0001635587,0.0001909156,0.0002992093,0.000953266],"category_scores_gemma":[0.00008893605,0.0001048551,0.0001552035,0.0001131573,0.0001318069,0.0001232161,0.0001189553,0.0003336351,0.0002492173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002594351,"about_ca_system_score_gemma":0.0002215991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005672635,"about_ca_topic_score_gemma":0.001022437,"domain_scores_codex":[0.9999105,0.00001278219,0.00000761271,0.00002122234,0.00002769077,0.00002026252],"domain_scores_gemma":[0.9999546,0.0000120871,0.00001121783,0.000005597631,0.000007907103,0.000008708762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002608816,0.0000254133,0.00002283314,0.00003056563,0.0000028743,0.00001551972,0.000006491478,0.00006688314,0.9980587,0.00007205192,0.00006023217,0.00161231],"study_design_scores_gemma":[0.00001169823,0.0002072999,0.0004311158,0.000002213265,0.000008832829,0.00005377219,0.000004251193,0.0006151173,0.9969398,0.00001345128,0.001710896,0.00000169007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818769,0.002917687,0.01050594,0.0002461763,0.0001011344,0.0001417964,0.0001953852,0.0001747022,0.003840339],"genre_scores_gemma":[0.9827497,0.001513893,0.01031099,0.0001479104,0.00001734319,0.0001108012,0.0002718623,0.00002694241,0.004850445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000953266,"threshold_uncertainty_score":0.003188968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191261505675834,"score_gpt":0.3303993188565953,"score_spread":0.3112731682890119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}