{"id":"W2585208686","doi":"10.1002/mabi.201600430","title":"Polymeric Delivery of siRNA against Integrin‐β1 (CD29) to Reduce Attachment and Migration of Breast Cancer Cells","year":2017,"lang":"en","type":"article","venue":"Macromolecular Bioscience","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society","keywords":"Integrin; Small interfering RNA; Cancer research; Breast cancer; Cancer cell; Fibronectin; Cell migration; Chemistry; Gene silencing; Cell biology; Cell adhesion; Cancer; Extracellular matrix; Cell; Biology; Medicine; Transfection; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002355563,0.0001412878,0.0002580505,0.0001820327,0.000139451,0.00004471398,0.00039076,0.00004728886,0.00004512743],"category_scores_gemma":[0.00007904267,0.0001212118,0.00007286955,0.0002671165,0.0004957183,0.00007478171,0.0003525267,0.0001160725,0.00000804819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006747452,"about_ca_system_score_gemma":0.0002091525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002096909,"about_ca_topic_score_gemma":0.00005877937,"domain_scores_codex":[0.9983779,0.00004213947,0.000266792,0.0004132831,0.0006166546,0.0002832294],"domain_scores_gemma":[0.9986416,0.00001767191,0.0001814954,0.0006760763,0.0002305608,0.0002526259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000961671,0.00009764018,0.005061329,0.00008732548,0.00001220739,0.00004157312,0.0001407782,0.000009089445,0.9723201,0.00001003345,0.0001258662,0.02199788],"study_design_scores_gemma":[0.000359071,0.000199637,0.09255543,0.0002107355,0.00001938896,0.00002566145,0.00006193222,0.000687198,0.9055471,0.000002295969,0.000228047,0.000103478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963791,0.0003940451,0.0004398812,0.001722224,0.00009214068,0.0003633346,0.00004506886,0.000008804732,0.0005554078],"genre_scores_gemma":[0.9978328,0.000379733,0.001153774,0.0003041355,0.00002169086,0.00001300146,0.000002926723,0.00001320841,0.0002787522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08749411,"threshold_uncertainty_score":0.4942876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191261505675834,"score_gpt":0.3303993188565953,"score_spread":0.3112731682890119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}