{"id":"W2585342837","doi":"10.1016/j.bpj.2016.11.1373","title":"The Role of the N-Terminal and S1 Segments in Kv1.5 Channel Trafficking and Modulation","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Cardiac Arrhythmias and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Extracellular; Potassium channel; Chemistry; Linker; Ion channel; Cleavage (geology); Amino acid; Biophysics; Voltage-gated potassium channel; Repolarization; Biochemistry; Biology; Electrophysiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003319004,0.0002302361,0.0002185719,0.0001396025,0.0002453931,0.0007314389,0.000248578,0.0004794204,0.001303909],"category_scores_gemma":[0.0005183351,0.0001028943,0.0003099263,0.00008056292,0.0003858426,0.001066809,0.0002603145,0.0004213985,0.000538773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003713274,"about_ca_system_score_gemma":0.0003410152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004824272,"about_ca_topic_score_gemma":0.0003747618,"domain_scores_codex":[0.9998543,0.00003854164,0.00001767852,0.00003038862,0.00002232807,0.00003680174],"domain_scores_gemma":[0.9997702,0.00006012294,0.00007056999,0.00001581308,0.0000439026,0.00003947443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001407175,0.00005792402,0.002369043,0.0001395388,0.00002594342,0.000367496,0.0002009659,0.0005347054,0.9794393,0.003113125,0.0003427673,0.01200201],"study_design_scores_gemma":[0.0001668234,0.001544118,0.08396973,0.0002307618,0.0001570966,0.003884813,0.001013484,0.01523273,0.8711583,0.00543888,0.01712951,0.00007370683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857328,0.00717784,0.00294713,0.0005707777,0.00006967369,0.00001464891,0.0001072665,0.00002956738,0.003350232],"genre_scores_gemma":[0.9943663,0.002594312,0.0009873522,0.0001828537,0.00003319639,0.000009808689,0.0001536698,0.00001824417,0.001654166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001303909,"threshold_uncertainty_score":0.004362047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096429234555484,"score_gpt":0.266030857089522,"score_spread":0.2550665647439671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}