{"id":"W2585783048","doi":"10.1182/blood.v108.11.3696.3696","title":"Overcoming Self-Tolerance: Long-Term Protection Against Specific erbB2-Expressing Prostate Tumors Using Low Doses of Lentivirus-Transduced DCs.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Immunotherapy; Cancer research; Medicine; Bone marrow; Viral vector; Immune tolerance; Antigen; CD86; Prostate cancer; Dendritic cell; Genetic enhancement; CD80; Immunology; Cancer; Biology; Cytotoxic T cell; T cell; Immune system; CD40; Internal medicine; In vitro; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002326673,0.0003324607,0.0002948331,0.0001482869,0.00009952453,0.0003858632,0.0002732015,0.0003937345,0.0007078322],"category_scores_gemma":[0.0001077859,0.0001038183,0.0002626777,0.0001176833,0.0002000987,0.0002381397,0.0001547595,0.001294393,0.0002240331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002056579,"about_ca_system_score_gemma":0.0002041482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003464009,"about_ca_topic_score_gemma":0.0003580784,"domain_scores_codex":[0.9998347,0.00002885183,0.00001524269,0.00003167944,0.00003291769,0.00005661038],"domain_scores_gemma":[0.9998738,0.00002701965,0.00002977495,0.00002414844,0.00001336123,0.00003192851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001281237,0.0001970109,0.00009781241,0.00003501289,0.000005536115,0.00001482755,0.00001361352,0.0000977599,0.9972039,0.00009608049,0.00005847518,0.002051785],"study_design_scores_gemma":[0.00005291169,0.00167992,0.001237802,0.000007534169,0.00002010367,0.0001205808,0.00001249652,0.001167455,0.9942777,0.00003469702,0.001385143,0.000003766213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912382,0.0009872506,0.005776852,0.0001339008,0.00007527411,0.00009756377,0.0003574419,0.0001812832,0.00115223],"genre_scores_gemma":[0.9948642,0.0004191483,0.002297995,0.00007324852,0.00002081017,0.00006318629,0.0003488408,0.0000227687,0.001889822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007078322,"threshold_uncertainty_score":0.002367973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307642205569893,"score_gpt":0.225940649284367,"score_spread":0.2128642272286681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}