{"id":"W2585891540","doi":"10.1016/j.bpj.2016.11.2072","title":"Mode of Action of Antimicrobial Peptides: Long and Short Amphipathic Alpha-Helixes Use Different Mechanisms","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Antimicrobial peptides; Membrane curvature; Peptide; Lipid bilayer; Chemistry; Circular dichroism; Membrane; Transmembrane protein; Amphiphile; Biophysics; Vesicle; Bilayer; Crystallography; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008420901,0.0005465929,0.0004848334,0.0002096307,0.0002579157,0.000814563,0.0005230575,0.0009696757,0.001161438],"category_scores_gemma":[0.0005281885,0.0002407032,0.0004406708,0.00007731932,0.0006189428,0.001283264,0.0003359458,0.0008899824,0.0006001559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002269187,"about_ca_system_score_gemma":0.0001349722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004511923,"about_ca_topic_score_gemma":0.00002902368,"domain_scores_codex":[0.9997415,0.00006509698,0.0000227381,0.00005035776,0.0000589754,0.0000613012],"domain_scores_gemma":[0.9996013,0.0001642149,0.00005959062,0.00003995292,0.00007209269,0.00006287191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004423998,0.00004399944,0.0004318682,0.0001504659,0.00001522365,0.0001209233,0.00007355572,0.0002141552,0.9929187,0.001158558,0.0001088151,0.004321335],"study_design_scores_gemma":[0.0001775103,0.001630319,0.005772185,0.00004322841,0.00006649056,0.001842006,0.0002052899,0.005999754,0.9791627,0.001889401,0.003157781,0.00005326773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756069,0.006471728,0.0139444,0.0004152428,0.0001343161,0.00009638433,0.0001299075,0.0001477743,0.003053204],"genre_scores_gemma":[0.9911165,0.001729121,0.005207927,0.0003055515,0.00005313083,0.0001006549,0.00007558669,0.00002448478,0.001386992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001161438,"threshold_uncertainty_score":0.00445348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03219534675051963,"score_gpt":0.280762010249512,"score_spread":0.2485666634989923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}