{"id":"W2586048965","doi":"10.1182/blood.v116.21.2001.2001","title":"Single Nucleotide Polymorphism Array (SNP-A) Genomic Profiling of Mantle Cell Lymphoma (MCL) Against a Large Control Database Reveals Recurring Copy Number Alterations (CNAs) and Copy Neutral Loss of Heterozygosity (CN-LOH)","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"SNP array; Loss of heterozygosity; Copy number analysis; Uniparental disomy; Biology; Molecular Inversion Probe; Copy-number variation; SNP genotyping; SNP; Genetics; Single-nucleotide polymorphism; Genotyping; Genotype; Chromosome; Karyotype; Genome; Gene; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003489309,0.0001510605,0.0002226739,0.001141106,0.0002662377,0.0003361258,0.000165308,0.0001731044,0.001516997],"category_scores_gemma":[0.0007945184,0.00007963504,0.0001479956,0.0007705273,0.0001369756,0.0001041875,0.0001998722,0.000176069,0.0002355051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001938542,"about_ca_system_score_gemma":0.0001366269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008789247,"about_ca_topic_score_gemma":0.001604749,"domain_scores_codex":[0.9996567,0.00004973862,0.00004208572,0.000127347,0.00009180567,0.00003239865],"domain_scores_gemma":[0.9995674,0.0001666782,0.0001149666,0.00003835592,0.00005333791,0.00005918214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001446155,0.0002168946,0.83377,0.00006917404,0.0002021875,0.0008406233,0.0001704287,0.0006471225,0.1349098,0.0001098752,0.0006245865,0.02699315],"study_design_scores_gemma":[0.00007610938,0.0005953595,0.9675039,0.000009113553,0.0001501427,0.003666888,0.00008574665,0.002501999,0.02384197,0.00008550348,0.001474764,0.000008563971],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983069,0.0001217548,0.0006680627,0.00001349476,0.000001512954,0.0000110188,0.0006541853,0.00002074922,0.0002023084],"genre_scores_gemma":[0.995905,0.00006805596,0.001289371,0.00002178423,0.000006454297,0.00002559059,0.00245501,0.000007996275,0.0002206711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516997,"threshold_uncertainty_score":0.005074859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006961417909067422,"score_gpt":0.2136840536564431,"score_spread":0.2067226357473756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}