{"id":"W2586088434","doi":"10.3390/ijms18020360","title":"Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome","year":2017,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Innovates","keywords":"Giant cell; Multinucleate; Radiosensitivity; Viability assay; Cancer cell; Biology; Cell culture; Apoptosis; Cell; Programmed cell death; Cancer research; Cancer; Molecular biology; Cell biology; Genetics; Radiation therapy; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000196679,0.0003121944,0.0003895318,0.0002111754,0.0001941989,0.0001796566,0.0001449016,0.0004398939,0.00111776],"category_scores_gemma":[0.0001728758,0.0000980332,0.0002780084,0.0001771737,0.0001934893,0.0001324602,0.0003772133,0.0003615042,0.0004478109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001677605,"about_ca_system_score_gemma":0.0001482115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000423834,"about_ca_topic_score_gemma":0.001188473,"domain_scores_codex":[0.9998827,0.00001723031,0.0000117409,0.00002729801,0.0000419506,0.00001894741],"domain_scores_gemma":[0.9997105,0.00006580188,0.00008522383,0.000051413,0.00003580853,0.00005129027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000294502,0.000005786753,0.0002476003,0.00003509437,0.000004340618,0.00006934703,0.00002494858,0.00002918454,0.9983137,0.0000464654,0.00002587072,0.001168341],"study_design_scores_gemma":[0.00001893002,0.0006951349,0.01617778,0.0000200814,0.00003138245,0.001421866,0.00009927632,0.0007389754,0.973026,0.0001658347,0.007593765,0.00001100221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9742788,0.003821772,0.01779996,0.0001447688,0.00007383686,0.0001600466,0.0009555948,0.000236447,0.002528674],"genre_scores_gemma":[0.9639335,0.002397622,0.02251565,0.0001502763,0.00002556894,0.0003046534,0.002339233,0.00006724399,0.008266248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00111776,"threshold_uncertainty_score":0.003739297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02522417103338043,"score_gpt":0.3183008397955074,"score_spread":0.293076668762127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}