{"id":"W2586259866","doi":"10.1182/blood.v116.21.1113.1113","title":"SAFETY of PROTHROMBIN COMPLEX CONCENTRATES IN PATIENTS REQUIRING RAPID REVERSAL of ANTICOAGULANT TREATMENT with the VITAMIN K ANTAGONISTS: a Systematic Review and a Meta-Analysis of the Literature.","year":2010,"lang":"en","type":"review","venue":"Blood","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph's Hospital","funders":"","keywords":"Medicine; Warfarin; Prothrombin complex concentrate; Concomitant; Internal medicine; Meta-analysis; Incidence (geometry); Coagulopathy; Fresh frozen plasma; Population; Vitamin K antagonist; Surgery; Complication; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01334114,0.002487081,0.01807053,0.009251757,0.0006355076,0.002681081,0.001830989,0.002383685,0.002687936],"category_scores_gemma":[0.03204409,0.00174023,0.03068852,0.009292594,0.0007811263,0.001616298,0.001344764,0.001344673,0.0003492977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002557618,"about_ca_system_score_gemma":0.003934523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005364553,"about_ca_topic_score_gemma":0.01377952,"domain_scores_codex":[0.9887908,0.004858532,0.00395682,0.00100338,0.001114274,0.0002763851],"domain_scores_gemma":[0.9737861,0.0171662,0.00567674,0.0006331924,0.00239571,0.0003420805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001966425,0.00003675462,0.005568974,0.4661765,0.5156175,0.0002203536,0.0001302754,0.0002947827,0.0003020034,0.00007993049,0.0005642091,0.009042217],"study_design_scores_gemma":[0.0007749921,0.0002997393,0.004471513,0.03304289,0.9597181,0.0001498456,0.00006986059,0.000164326,0.0001342053,0.00009277258,0.00105413,0.0000275761],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01068685,0.9870591,0.0004726393,0.0002399318,0.0001751817,0.000526832,0.0005965215,0.0000192136,0.0002237379],"genre_scores_gemma":[0.2382769,0.7547963,0.00256466,0.000952077,0.0003122526,0.001788147,0.0009225084,0.00002876112,0.0003583784],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01807053,"threshold_uncertainty_score":0.07055557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08356736140687229,"score_gpt":0.3386702739045945,"score_spread":0.2551029124977222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}