{"id":"W2586300645","doi":"10.1016/j.neubiorev.2017.01.046","title":"Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer's disease: the emerging role for microglia?","year":2017,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":124,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"National Institute on Aging","keywords":"Neuroinflammation; Microglia; Neurodegeneration; Neuroscience; Cognitive decline; TREM2; Psychology; Alzheimer's disease; Chronic stress; Medicine; Disease; Dementia; Inflammation; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000696847,0.001025579,0.001823073,0.001086521,0.0003085406,0.001338757,0.0009654017,0.001380171,0.003372414],"category_scores_gemma":[0.0007666601,0.0001986382,0.0005457641,0.001513625,0.0005640488,0.001182563,0.000933743,0.001549822,0.001254181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004330841,"about_ca_system_score_gemma":0.00131911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001758571,"about_ca_topic_score_gemma":0.002802235,"domain_scores_codex":[0.9998358,0.00003136682,0.00002506638,0.00002829457,0.00005600798,0.00002342731],"domain_scores_gemma":[0.9997546,0.00009412895,0.00004252666,0.000008159443,0.00007196786,0.00002861379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002063804,0.00008444469,0.0003980481,0.01883782,0.0001981343,0.0002312623,0.0001046242,0.0002014787,0.001454101,0.002784965,0.02702061,0.9484781],"study_design_scores_gemma":[0.00006922902,0.0002539717,0.003822384,0.01401348,0.000585145,0.001484871,0.0003259843,0.0001276293,0.0005313659,0.005449321,0.9732832,0.0000533369],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007389932,0.9993699,0.00002528618,0.0001995367,0.0001232241,0.000001475327,0.00000980912,0.000001803649,0.0001950997],"genre_scores_gemma":[0.000404072,0.9991465,0.0000383496,0.00008512248,0.0001648573,0.000002434579,0.00001041677,3.762119e-7,0.0001479631],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003372414,"threshold_uncertainty_score":0.01128179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2533303015916775,"score_gpt":0.4369453215180632,"score_spread":0.1836150199263857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}