{"id":"W2586313031","doi":"10.1182/blood.v126.23.3983.3983","title":"Updated Results of a Phase I Study of Ibrutinib and Lenalidomide in Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Lenalidomide; Medicine; Ibrutinib; Mantle cell lymphoma; Neutropenia; Internal medicine; Febrile neutropenia; Gastroenterology; Rituximab; Tumor lysis syndrome; Lymphoma; Oncology; Multiple myeloma; Toxicity; Chemotherapy; Leukemia; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004798748,0.0006984333,0.002426612,0.0003748623,0.0003054907,0.001097148,0.0008469336,0.0007401286,0.001281317],"category_scores_gemma":[0.003358669,0.0004746599,0.001152916,0.000570574,0.0003451352,0.0008102414,0.0003483157,0.001561378,0.0003989241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008183386,"about_ca_system_score_gemma":0.001026309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001312864,"about_ca_topic_score_gemma":0.002253666,"domain_scores_codex":[0.9980897,0.001127377,0.000181602,0.0001941296,0.000253141,0.0001539259],"domain_scores_gemma":[0.997678,0.0007337329,0.0004993129,0.00016443,0.0002254842,0.0006990823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4259691,0.02316428,0.253767,0.0009316759,0.008228055,0.0009634095,0.000931068,0.003294476,0.0346787,0.0001733768,0.004761431,0.2431375],"study_design_scores_gemma":[0.2452904,0.2650007,0.4599174,0.0001162676,0.007402285,0.0017507,0.0002789945,0.002357053,0.005584176,0.0002110113,0.01200675,0.00008416284],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915963,0.00420344,0.0003329104,0.0003347301,0.00005170242,0.000646073,0.001091571,0.00004853609,0.001694752],"genre_scores_gemma":[0.9925262,0.001204041,0.0008380334,0.0006663673,0.0001483927,0.0004727318,0.003560841,0.00001592848,0.0005675395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004798748,"threshold_uncertainty_score":0.02537853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01712260056935359,"score_gpt":0.284229050499581,"score_spread":0.2671064499302274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}