{"id":"W2586506104","doi":"10.3389/fimmu.2017.00094","title":"GTPase of the Immune-Associated Nucleotide Protein 5 Regulates the Lysosomal Calcium Compartment in T Lymphocytes","year":2017,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Immune system; GTPase; Cell biology; Compartment (ship); Nucleotide; Calcium; Lysosome; Biology; Chemistry; Immunology; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008802716,0.0003948644,0.0001995806,0.0004002374,0.0001338157,0.0002977528,0.0002093361,0.000432515,0.0007321568],"category_scores_gemma":[0.0001346606,0.0001560052,0.0002369647,0.0001463997,0.0003544826,0.0002228118,0.0002751907,0.0004609729,0.0002389674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002260804,"about_ca_system_score_gemma":0.000119836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002766636,"about_ca_topic_score_gemma":0.0002771356,"domain_scores_codex":[0.9998837,0.00002372713,0.00001028012,0.00002850252,0.00002303575,0.00003079997],"domain_scores_gemma":[0.9998671,0.00001604608,0.00005872036,0.00001189681,0.000008925144,0.00003728399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009627864,0.000005618441,0.0002315985,0.000008978423,0.00000181063,0.0001061122,0.000008462317,0.00003713855,0.9991843,0.00004647502,0.000009840661,0.0002634235],"study_design_scores_gemma":[0.0000327364,0.0001883478,0.01523678,0.000007304255,0.00002840986,0.0008037118,0.00008489176,0.001684756,0.9807767,0.0001599418,0.0009888361,0.000007585676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982186,0.0003419914,0.0009675965,0.00005205268,0.000006327414,0.000003857935,0.0001067769,0.00005284356,0.0002499098],"genre_scores_gemma":[0.9982622,0.0002678848,0.0005476051,0.00001899038,0.000004220791,0.0000151298,0.0001741053,0.00001769146,0.0006921795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007321568,"threshold_uncertainty_score":0.002449274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01026969982294676,"score_gpt":0.2340201408431788,"score_spread":0.223750441020232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}