{"id":"W2586515949","doi":"10.1182/blood.v106.11.4332.4332","title":"Overexpression of MEL1 as a Novel Fusion Partner of AML1 in the Blastic Phase of Chronic Myeloid Leukemia with the Recurrent Cryptic Translocation t(1;21)(p36.3;q22).","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Chromosomal translocation; Biology; Myeloid leukemia; Molecular biology; Fusion gene; Gene; Intron; RNA splicing; Genetics; Cancer research; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008965864,0.0002509996,0.000116367,0.0001710076,0.0001685465,0.0002103308,0.000115015,0.0003401859,0.0007697388],"category_scores_gemma":[0.00009932486,0.000113512,0.0001529676,0.0001303833,0.0001885283,0.0001149788,0.0001589903,0.0002927071,0.0003282543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004370156,"about_ca_system_score_gemma":0.0001345717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006512024,"about_ca_topic_score_gemma":0.0007956753,"domain_scores_codex":[0.9999249,0.000009674541,0.000006851855,0.00001705207,0.00002149068,0.00002013129],"domain_scores_gemma":[0.9999306,0.00001300215,0.00001854858,0.000007596394,0.000004674757,0.00002555154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002956317,0.000006493026,0.0001797877,0.000007716147,0.000001087322,0.0002820037,0.00001202411,0.00003351901,0.9991578,0.00005048358,0.0000107829,0.0002287952],"study_design_scores_gemma":[0.00003404355,0.0003755339,0.01265842,0.000004294224,0.00001923193,0.004577325,0.00006430518,0.00213944,0.9761781,0.00007460855,0.003868269,0.000006315274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986532,0.0002187842,0.0005438871,0.00004402741,0.000007838034,0.00001175903,0.000136862,0.00002861497,0.0003550431],"genre_scores_gemma":[0.9980818,0.0001136795,0.0005386314,0.00001458076,0.000003049938,0.000008080749,0.0002954286,0.000006940114,0.0009377575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007697388,"threshold_uncertainty_score":0.003170848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008980958979688263,"score_gpt":0.2606692032297662,"score_spread":0.2516882442500779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}