{"id":"W2586528038","doi":"10.1016/s0923-7534(21)00568-8","title":"410P Ipilimumab efficacy and safety profile in metastatic melanoma in Saskatchewan","year":2016,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Ipilimumab; Medicine; Internal medicine; Melanoma; Adverse effect; Oncology; Metastatic melanoma; Retrospective cohort study; Confidence interval; Surgery; Immunotherapy; Cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004850035,0.0002134683,0.0002337194,0.0003960665,0.0005381805,0.0006018153,0.0004029113,0.0002256587,0.002175177],"category_scores_gemma":[0.0005236694,0.0001738557,0.0002253343,0.0008240337,0.0002738901,0.000252403,0.0003308702,0.0006196024,0.0006344017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005210458,"about_ca_system_score_gemma":0.005836131,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.4296563,"about_ca_topic_score_gemma":0.6617926,"domain_scores_codex":[0.9997659,0.00004211481,0.00001613412,0.0000414963,0.0000626324,0.0000716268],"domain_scores_gemma":[0.9996308,0.00004790767,0.00004817652,0.00002591758,0.0001288625,0.0001183907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02160985,0.003587015,0.5437259,0.0002889702,0.0006148478,0.002484598,0.001162685,0.003704767,0.1522768,0.0008981316,0.01295162,0.2566948],"study_design_scores_gemma":[0.001371497,0.006047519,0.9683006,0.00005807434,0.0003266625,0.0007945589,0.0009988786,0.001801335,0.01084809,0.000205008,0.009192855,0.00005486567],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930794,0.0004540436,0.0001172036,0.0004024706,0.00001210396,0.00007212337,0.001047005,0.00001665977,0.004799021],"genre_scores_gemma":[0.9931994,0.0008152015,0.0001703677,0.0004762423,0.000008411758,0.00007232655,0.001073011,0.000009126855,0.00417581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5703437,"threshold_uncertainty_score":0.8543109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08230944959589033,"score_gpt":0.4061339372627542,"score_spread":0.3238244876668638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}