{"id":"W2586566142","doi":"10.1038/ncomms14360","title":"FAK signalling controls insulin sensitivity through regulation of adipocyte survival","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; University of California, San Francisco; Banting and Best Diabetes Centre, University of Toronto; Novo Nordisk; Canadian Liver Foundation","keywords":"Adipocyte; Adipose tissue; Internal medicine; Endocrinology; Insulin resistance; Focal adhesion; Context (archaeology); Insulin receptor; Biology; Insulin; Signal transduction; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007861528,0.0002148109,0.0001272491,0.0001710653,0.0001421826,0.0003550164,0.0001046227,0.0001532375,0.001222689],"category_scores_gemma":[0.00007423513,0.00011172,0.0001250331,0.0001374262,0.0001757868,0.0001831014,0.0002075599,0.0003306047,0.0002966747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002203608,"about_ca_system_score_gemma":0.00009452254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003047184,"about_ca_topic_score_gemma":0.0005216281,"domain_scores_codex":[0.9999115,0.00001613007,0.000005774657,0.00001878735,0.00001879629,0.00002898983],"domain_scores_gemma":[0.99994,0.000006556411,0.00002358152,0.000005847247,0.000005818461,0.00001814262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003043346,0.00001049508,0.0005504927,0.00002389455,0.000004650929,0.00004380039,0.00001108859,0.00003750854,0.9965441,0.0001361929,0.00005447674,0.002279012],"study_design_scores_gemma":[0.00005866337,0.0004218232,0.07404508,0.00002195789,0.00004675348,0.0006006831,0.0001350785,0.001763461,0.9159513,0.0003680807,0.006568417,0.00001875802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993519,0.002954141,0.001226597,0.0001821445,0.00002793852,0.000005712259,0.0002211792,0.00004819188,0.001815032],"genre_scores_gemma":[0.996531,0.001427236,0.0004918351,0.00004201259,0.00000886301,0.000008437865,0.0001213978,0.00001003643,0.001359248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001222689,"threshold_uncertainty_score":0.004090309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06311150739460827,"score_gpt":0.3823521867577771,"score_spread":0.3192406793631688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}