{"id":"W2586627998","doi":"10.2174/1566523217666170102111251","title":"Antibody Delivery Mediated by Recombinant Adeno-associated Virus for the Treatment of Various Chronic and Infectious Diseases","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Université Laval","funders":"","keywords":"Monoclonal antibody; Medicine; Antibody; Virus; Immunology; Virology; Genetic enhancement; Adeno-associated virus; Vector (molecular biology); Immune system; Disease; Recombinant DNA; Biology; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003368585,0.0006496828,0.0007405586,0.001726934,0.0001862119,0.0005775421,0.0005541415,0.0006583337,0.002671904],"category_scores_gemma":[0.0002489221,0.0002036057,0.000401504,0.001292763,0.0002626389,0.0007743377,0.0004260604,0.00121724,0.001952472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004284336,"about_ca_system_score_gemma":0.0005977546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000574084,"about_ca_topic_score_gemma":0.0008343271,"domain_scores_codex":[0.9998783,0.00001649375,0.00001515796,0.00002047343,0.00005704048,0.00001246302],"domain_scores_gemma":[0.9999272,0.00002763493,0.00001232543,0.00000328118,0.00002073463,0.000008936567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000590663,0.00009845326,0.0001362074,0.01564395,0.00008110965,0.0003012897,0.00006854902,0.0004250782,0.01599094,0.004824894,0.02061187,0.9417586],"study_design_scores_gemma":[0.00001116132,0.00008329181,0.000411166,0.001013219,0.00006781088,0.00108776,0.00002201296,0.00008844814,0.003019341,0.0009478144,0.9932334,0.00001447404],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003654657,0.9965424,0.000559943,0.0001536633,0.0002007876,0.00001133937,0.00002839619,0.00001944658,0.002118609],"genre_scores_gemma":[0.001337503,0.9967672,0.000463,0.0001157634,0.00007172018,0.00001269182,0.00005014067,0.000003140763,0.001178804],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002671904,"threshold_uncertainty_score":0.008938372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06438738618525104,"score_gpt":0.3993344334318936,"score_spread":0.3349470472466426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}