{"id":"W2586859590","doi":"10.1182/blood.v114.22.31.31","title":"Novel Mechanistic Insight Into Mobilization of Hematopoietic Stem/Progenitor Cells (HSPCs): Complement Cascade and Membrane Attack Complex Activated in Bone Marrow Sinusoids During Mobilization Release From Erythrocytes Sphingosine-1 Phosphate – An Underappreciated Chemoattractant Executing Egress of HSPCs.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Haematopoiesis; Bone marrow; Progenitor cell; Complement membrane attack complex; Cell biology; Chemistry; Myelopoiesis; Complement system; Stem cell; Immunology; Biology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462394,0.0002928466,0.0001888911,0.0001891526,0.0001611499,0.0002978008,0.000162742,0.0004121236,0.001769854],"category_scores_gemma":[0.00005900022,0.00008916583,0.0001623073,0.00008851967,0.0002311154,0.000408976,0.0003069894,0.0004461818,0.0002463888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002939395,"about_ca_system_score_gemma":0.0002250944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002358246,"about_ca_topic_score_gemma":0.0003041261,"domain_scores_codex":[0.999941,0.00001101263,0.000003397784,0.000009218552,0.00001334719,0.0000219108],"domain_scores_gemma":[0.999976,0.000002681267,0.000006885884,0.000001833568,0.000003715917,0.000008796452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002392047,0.000026548,0.0004151903,0.0001381735,0.000006696177,0.0004872295,0.00004364649,0.00007078001,0.9942328,0.001398489,0.0001844887,0.002756725],"study_design_scores_gemma":[0.000100666,0.0007636662,0.03388938,0.00006025829,0.0000624055,0.003455503,0.0004224295,0.004451061,0.9360942,0.003162385,0.01751777,0.00002022249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9629653,0.02136291,0.0094879,0.001521086,0.00009822632,0.000102762,0.0003579907,0.00008621868,0.004017574],"genre_scores_gemma":[0.9905121,0.004362278,0.002668133,0.0002436732,0.00006123365,0.00003798264,0.0002060329,0.00000550983,0.001903013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001769854,"threshold_uncertainty_score":0.005920708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02928521248660082,"score_gpt":0.2671580597054164,"score_spread":0.2378728472188156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}