{"id":"W2587188409","doi":"10.1097/pai.0000000000000477","title":"Detection of Novel t(12;17)(p12;p13) in Relapsed Refractory Acute Myeloid Leukemia by Anchored Multiplex PCR(AMP)-based Next-Generation Sequencing","year":2017,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brandon Regional Health Authority","funders":"","keywords":"Medicine; Myeloid leukemia; Fusion transcript; Fusion gene; Myelodysplastic syndromes; Multiplex; NPM1; Leukemia; Oncology; Internal medicine; Cancer research; Karyotype; Bioinformatics; Biology; Gene; Bone marrow; Genetics; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002090612,0.0002463502,0.0002178092,0.0005551716,0.0001238751,0.0003273558,0.0002294614,0.0005450774,0.0006166735],"category_scores_gemma":[0.0004578265,0.0001307836,0.000163277,0.0002703572,0.0001553887,0.0001354048,0.0001859967,0.0003078557,0.0002050053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001523251,"about_ca_system_score_gemma":0.00007076987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003080011,"about_ca_topic_score_gemma":0.0004752527,"domain_scores_codex":[0.9998249,0.00002387354,0.00001605607,0.0000588061,0.00005025177,0.00002604341],"domain_scores_gemma":[0.9998763,0.00003917274,0.00003829714,0.000008750803,0.00002048081,0.00001706796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000554618,0.00006831315,0.05093968,0.0001311202,0.00002931971,0.00941637,0.000258576,0.0008553282,0.8999349,0.0002436353,0.000315442,0.03725275],"study_design_scores_gemma":[0.00007901207,0.001692914,0.1674129,0.00007337722,0.0002515485,0.06725993,0.0005602947,0.03406117,0.7175639,0.001313475,0.009688918,0.00004250184],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886686,0.0007809332,0.009076815,0.0001007408,0.00001208742,0.0000654313,0.0005876921,0.0001135864,0.0005940038],"genre_scores_gemma":[0.9850975,0.00048854,0.01327271,0.00009093976,0.00001007698,0.00004043626,0.0004747288,0.000009693269,0.0005154163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006166735,"threshold_uncertainty_score":0.002062976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03879085035014108,"score_gpt":0.2951051405358488,"score_spread":0.2563142901857077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}