{"id":"W2587213758","doi":"10.1093/ecco-jcc/jjx002.058","title":"DOP021 Long-term effectiveness and safety of vedolizumab in patients with Crohn's disease: 5-year cumulative exposure of GEMINI 2 completers rolling into the GEMINI open-label extension study","year":2017,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Robarts Clinical Trials; Western University","funders":"","keywords":"Vedolizumab; Medicine; Internal medicine; Adverse effect; Ulcerative colitis; Inflammatory bowel disease; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002623311,0.0003716041,0.0008555786,0.0002384905,0.0002013335,0.0006802081,0.0002505188,0.0004689159,0.001829255],"category_scores_gemma":[0.001790575,0.000158851,0.001040301,0.0002565508,0.0002414645,0.0005446172,0.000313389,0.0009273434,0.0003152932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000418637,"about_ca_system_score_gemma":0.0004051528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002520418,"about_ca_topic_score_gemma":0.0005666675,"domain_scores_codex":[0.9991977,0.0004041697,0.00007258903,0.000103648,0.0001283964,0.0000936106],"domain_scores_gemma":[0.9988546,0.0002705604,0.0004334868,0.00008055513,0.00009534826,0.0002653278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7139725,0.01269186,0.1452203,0.0008298326,0.003219934,0.0002432271,0.0002721336,0.001806788,0.01868503,0.0001466922,0.001688147,0.1012236],"study_design_scores_gemma":[0.07736024,0.4948675,0.4119891,0.00009761916,0.003159177,0.0004992503,0.0001786104,0.002177283,0.004669052,0.0001910808,0.004755396,0.00005574226],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970149,0.001273128,0.0001487169,0.00007211589,0.00001823754,0.0001282088,0.0006637611,0.000007284051,0.000673608],"genre_scores_gemma":[0.9974928,0.0003445958,0.0001851566,0.0000917975,0.00004655928,0.000119659,0.001187762,0.000002445112,0.0005291329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002623311,"threshold_uncertainty_score":0.01387352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02820483236420604,"score_gpt":0.3226132764318975,"score_spread":0.2944084440676914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}