{"id":"W2587219500","doi":"10.1136/annrheumdis-2016-210503","title":"Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS)","year":2017,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Pharmacyclics; Genentech; Medac; Gilead Sciences; European League Against Rheumatism; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; CSL Behring; Array BioPharma; Sanofi; Scleroderma and Raynaud's UK; Pfizer; Active Biotech; Celgene","keywords":"Medicine; Scleroderma (fungus); Observational study; Dermatology; Outcome (game theory); Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003963854,0.0002901624,0.0006312931,0.00007638559,0.0004964974,0.0001490571,0.0008095516,0.00004641855,0.0000244668],"category_scores_gemma":[0.000928539,0.0001397231,0.000437638,0.0001261444,0.0002375739,0.0001408747,0.0002046771,0.0001103575,0.0000553986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005748991,"about_ca_system_score_gemma":0.0001163954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008911643,"about_ca_topic_score_gemma":0.00002695631,"domain_scores_codex":[0.9972109,0.0005659998,0.0009431934,0.0003209019,0.0006467127,0.0003123126],"domain_scores_gemma":[0.9967875,0.0002882949,0.0006967863,0.001889191,0.0001514875,0.0001866852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001416741,0.002700716,0.9807096,0.0001853393,0.0005019988,0.00003515527,0.001355388,0.00008050351,0.00007712178,0.00005172736,0.0004495827,0.01371117],"study_design_scores_gemma":[0.002851407,0.0002509071,0.9892433,0.005382536,0.0005146402,0.00004357749,0.001255923,0.0002069055,0.0000358609,0.00006110211,0.000009572748,0.0001442862],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907247,0.004111636,0.000001183009,0.00242812,0.0002953023,0.001664462,0.00007934387,0.00004516991,0.0006500979],"genre_scores_gemma":[0.997846,0.00119293,0.000003183965,0.0002329586,0.00007887451,0.0001092904,0.000007821007,0.00004053747,0.0004884098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01356688,"threshold_uncertainty_score":0.5697743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2372845424958659,"score_gpt":0.3533893585259062,"score_spread":0.1161048160300404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}