{"id":"W2587435215","doi":"10.1080/2162402x.2017.1287247","title":"The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis","year":2017,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Carcinogenesis; Cancer research; Metastasis; Cancer; Breast cancer; Medicine; Mammary tumor; Inflammation; Interleukin 6; Biology; Immunology; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001912547,0.000709185,0.0003046467,0.0003791694,0.0002036884,0.0003778941,0.0002014001,0.0002666128,0.001569687],"category_scores_gemma":[0.0001488452,0.0001482077,0.0002631477,0.0001199864,0.0003962154,0.0002120624,0.0002903,0.0007995234,0.0004838731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003140919,"about_ca_system_score_gemma":0.0002690771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000193675,"about_ca_topic_score_gemma":0.0002832786,"domain_scores_codex":[0.9997582,0.00004370744,0.00001545799,0.00004513427,0.00007924788,0.00005817383],"domain_scores_gemma":[0.9997978,0.00001628257,0.0001075137,0.00001527236,0.00001321132,0.00004994816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009404461,0.00002255764,0.0004371062,0.00003996184,0.00000288095,0.00009003803,0.000008966721,0.000065921,0.9971704,0.0002177548,0.00007238141,0.001778085],"study_design_scores_gemma":[0.0000368269,0.0004187856,0.02045392,0.0000270839,0.00002262742,0.001679953,0.00006767008,0.001101752,0.9688562,0.0002661069,0.007060503,0.000008519995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772131,0.01015075,0.007643444,0.0006305069,0.00007928903,0.00004607934,0.0008027888,0.0003367341,0.0030973],"genre_scores_gemma":[0.9913614,0.00315989,0.001828857,0.00006787072,0.00002447593,0.00004199097,0.0004623857,0.00002821367,0.003024913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001569687,"threshold_uncertainty_score":0.00525111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01501972708692082,"score_gpt":0.2600620662682379,"score_spread":0.2450423391813171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}