{"id":"W2587512795","doi":"10.1161/jaha.116.004738","title":"Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion","year":2017,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Myocardial infarction; Cardiology; Ischemia; Ligation; Cardiac function curve; Internal medicine; Apoptosis; Myocyte; Reperfusion injury; Cardiac myocyte; Infarction; Heart failure; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005609948,0.0001005947,0.0003586902,0.00002156576,0.000171374,0.00004880591,0.0001711305,0.00007315807,0.000003367316],"category_scores_gemma":[0.0009603731,0.00006997872,0.0003518273,0.00003968301,0.0001115043,0.00002008896,0.0001875309,0.0001229373,5.564301e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004192486,"about_ca_system_score_gemma":0.0000625385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000105003,"about_ca_topic_score_gemma":9.883529e-7,"domain_scores_codex":[0.9990483,0.0001529745,0.0002487266,0.0001226346,0.0002910713,0.000136317],"domain_scores_gemma":[0.9985041,0.00005096705,0.0009079053,0.0002762637,0.0002086103,0.00005214263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001370079,0.00001264742,0.2217165,0.000004076472,0.0001106067,1.073783e-7,0.00004142183,0.00000443319,0.7746587,3.133222e-7,0.002153559,0.001160645],"study_design_scores_gemma":[0.0002025835,0.0001701304,0.2967019,0.00005657521,0.00005162252,0.000003068454,0.00006243019,0.000002250035,0.6988692,0.0000123335,0.003798763,0.00006906265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982504,0.0003285628,0.000002622395,0.0009462264,0.0002416153,0.00008337642,0.00001892743,0.000001556865,0.0001267751],"genre_scores_gemma":[0.9983232,0.0004396459,0.0002768966,0.0001624551,0.0006236489,0.000003888639,9.544359e-7,0.00001102905,0.0001582531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07578947,"threshold_uncertainty_score":0.285365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0052452380009153,"score_gpt":0.2496599623139697,"score_spread":0.2444147243130544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}