{"id":"W2587512795","doi":"10.1161/jaha.116.004738","title":"Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion","year":2017,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Myocardial infarction; Cardiology; Ischemia; Ligation; Cardiac function curve; Internal medicine; Apoptosis; Myocyte; Reperfusion injury; Cardiac myocyte; Infarction; Heart failure; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001585329,0.0005632911,0.0004727848,0.0003014441,0.0001242571,0.000208778,0.0002356514,0.0004151096,0.001191796],"category_scores_gemma":[0.0001239064,0.0001600521,0.0002462643,0.0001384452,0.0003230981,0.0001913577,0.0001565932,0.0006028825,0.0003552845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002405642,"about_ca_system_score_gemma":0.0002098651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002904936,"about_ca_topic_score_gemma":0.0004993263,"domain_scores_codex":[0.9999127,0.00001246209,0.00001070866,0.00001724842,0.00002144869,0.00002537368],"domain_scores_gemma":[0.9998513,0.00001280701,0.00005629566,0.00001460329,0.00001333428,0.00005163173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003807585,0.0001123066,0.0001142607,0.00003759735,0.000006273173,0.00001902545,0.000006702935,0.00004599623,0.9978097,0.00002338838,0.00002980837,0.001414083],"study_design_scores_gemma":[0.0001372182,0.002039994,0.004610574,0.00001224789,0.00004360554,0.0001500034,0.00002083667,0.0009390339,0.9909402,0.00003602214,0.001065857,0.000004428545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963447,0.001358587,0.001370435,0.0001163717,0.0000391721,0.00002034299,0.0001099404,0.0001449312,0.00049538],"genre_scores_gemma":[0.9941743,0.0012859,0.001927101,0.00005133921,0.00002178764,0.0000478409,0.0002888372,0.00003127729,0.002171591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191796,"threshold_uncertainty_score":0.003986955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0052452380009153,"score_gpt":0.2496599623139697,"score_spread":0.2444147243130544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}