{"id":"W2587599577","doi":"10.1093/neuonc/now212.018","title":"ACTR-19. BASELINE PLASMA MATRIX METALLOPROTEINASE 9 (MMP9) PREDICTS OVERALL SURVIVAL (OS) BENEFIT FROM BEVACIZUMAB INDEPENDENTLY OF MOLECULAR SUBTYPES IN NEWLY DIAGNOSED GLIOBLASTOMA: RETROSPECTIVE ANALYSIS OF AVAglio","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Princess Margaret Cancer Centre","funders":"","keywords":"Bevacizumab; Temozolomide; Medicine; Internal medicine; Placebo; Oncology; MMP9; MMP2; Univariate analysis; Post-hoc analysis; Retrospective cohort study; Gastroenterology; Multivariate analysis; Chemotherapy; Pathology; Cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007366978,0.0001791306,0.0004579638,0.0002834796,0.0001431235,0.0003275574,0.000264748,0.0002364158,0.0007599544],"category_scores_gemma":[0.0009995356,0.0002008329,0.0004962211,0.0003252628,0.0002237841,0.0002195138,0.0001735038,0.0003387183,0.000185458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002988846,"about_ca_system_score_gemma":0.0001982844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007582624,"about_ca_topic_score_gemma":0.001680783,"domain_scores_codex":[0.999466,0.0001236475,0.0000650799,0.0001726235,0.0001227693,0.00004998633],"domain_scores_gemma":[0.9991856,0.0001757566,0.0003516678,0.00008209267,0.00005966784,0.0001451973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01165863,0.0001768045,0.9678245,0.00007327431,0.0004972901,0.0003353458,0.00006747455,0.0001757969,0.009056224,0.00004021093,0.0003213063,0.009773178],"study_design_scores_gemma":[0.0002820663,0.002287005,0.9937596,0.000006365712,0.0002487225,0.0009143209,0.00002912564,0.0005351041,0.001129681,0.00005534824,0.0007465467,0.000006012674],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986481,0.0005273145,0.0001557523,0.00001350817,0.000005449306,0.0000243259,0.0003912226,0.00000387943,0.0002303239],"genre_scores_gemma":[0.9991236,0.00008180412,0.00009813874,0.00001805093,0.000008175511,0.00002576832,0.0005079211,0.000002904185,0.0001336349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007599544,"threshold_uncertainty_score":0.003896058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01112914385499897,"score_gpt":0.273743561139056,"score_spread":0.262614417284057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}