{"id":"W2587649883","doi":"10.1007/978-1-4939-6759-9_17","title":"Multiplex Immunohistochemistry for Mapping the Tumor Microenvironment","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Multiplex; Immunohistochemistry; Tumor microenvironment; Signal transduction; Cell biology; Computational biology; Biology; Cancer research; Bioinformatics; Tumor cells; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008453397,0.0008146352,0.0004058814,0.001186081,0.0004431809,0.0009041202,0.0005692355,0.0005552407,0.002932631],"category_scores_gemma":[0.0005629165,0.0005410492,0.0002723929,0.0005735975,0.0003268873,0.000889245,0.0006896644,0.000924734,0.0009190106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004898998,"about_ca_system_score_gemma":0.0002540888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006241383,"about_ca_topic_score_gemma":0.001721436,"domain_scores_codex":[0.999449,0.0001043533,0.00002404978,0.0001865586,0.0001497658,0.00008626886],"domain_scores_gemma":[0.999588,0.000132079,0.00007945421,0.00007140013,0.00007097487,0.00005808101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000115755,0.00005117722,0.001774136,0.0000835511,0.00003305807,0.0000558125,0.0000440356,0.0002190001,0.9726044,0.001313664,0.0004604552,0.02324496],"study_design_scores_gemma":[0.00004347847,0.0003909951,0.01335714,0.00004234612,0.0001808962,0.001104958,0.00008881983,0.01920848,0.9507176,0.002120989,0.01269965,0.00004474062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3455313,0.01399367,0.6253663,0.0005301063,0.0003086744,0.0003235907,0.001485422,0.001616006,0.01084491],"genre_scores_gemma":[0.6396228,0.006591029,0.3383417,0.0003864197,0.000304397,0.0007676368,0.0008919422,0.0001633401,0.01293094],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002932631,"threshold_uncertainty_score":0.009810627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0291283672710968,"score_gpt":0.3680002662557464,"score_spread":0.3388718989846496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}