{"id":"W2587752484","doi":"10.1002/1873-3468.12592","title":"Dioleoyl‐phosphatidic acid selectively binds to α‐synuclein and strongly induces its aggregation","year":2017,"lang":"en","type":"letter","venue":"FEBS Letters","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Japan Science and Technology Agency; Daiwa Securities Health Foundation; Daiichi Sankyo Foundation of Life Science; Ministry of Education, Culture, Sports, Science and Technology; Japan Foundation for Applied Enzymology; Naito Foundation","keywords":"Phosphatidic acid; Chemistry; Biophysics; Cell biology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002370191,0.0004217821,0.0003224285,0.0002164435,0.0004950768,0.0007404153,0.0002708603,0.004157057,0.002792065],"category_scores_gemma":[0.001420836,0.0001376806,0.0001785849,0.000179905,0.0006017382,0.0004012084,0.0002687367,0.002754184,0.003012734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000993956,"about_ca_system_score_gemma":0.0003253806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003481806,"about_ca_topic_score_gemma":0.0005190713,"domain_scores_codex":[0.9997688,0.00007268298,0.00002293946,0.00003421312,0.00006401448,0.00003741196],"domain_scores_gemma":[0.9995963,0.0001591508,0.00005450442,0.00003394409,0.00009795977,0.00005822035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00456006,0.0008860667,0.01129722,0.001318402,0.0001395384,0.128929,0.0004378286,0.0004891391,0.1660558,0.01556717,0.4501123,0.2202074],"study_design_scores_gemma":[0.0005406891,0.001043627,0.007101096,0.0001580428,0.00008431087,0.05997345,0.000417538,0.001836451,0.07199699,0.009673035,0.847129,0.00004568205],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2079891,0.06391676,0.003265462,0.5966398,0.04238109,0.0002164011,0.0005018787,0.0006646339,0.08442494],"genre_scores_gemma":[0.6757808,0.0523426,0.003582711,0.1374227,0.0353469,0.0002445019,0.0006503185,0.00008291753,0.09454662],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004157057,"threshold_uncertainty_score":0.009340346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02145211424411653,"score_gpt":0.2632661249234419,"score_spread":0.2418140106793254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}