{"id":"W2587810005","doi":"10.1182/blood.v128.22.2992.2992","title":"Serum Biomarkers Predict Outcomes in Advanced Hodgkin Lymphoma Independent of International Prognostic Score (IPS) and Treatment: Correlative Analysis from a Large North American Cooperative Group Trial","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Internal medicine; Medicine; Oncology; CD163; International Prognostic Index; Chemokine; Nodular sclerosis; Immunology; CXCL9; CD68; Lymphoma; Chemokine receptor; Rituximab; Receptor; Hodgkin lymphoma; Biology; Phenotype; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007579931,0.001179604,0.002232285,0.0004945134,0.0005849341,0.001456822,0.001189894,0.001274679,0.001710132],"category_scores_gemma":[0.005563727,0.0005287258,0.001680317,0.001205862,0.001244862,0.001019966,0.0007910912,0.001473322,0.0002944357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008476413,"about_ca_system_score_gemma":0.001462496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001606473,"about_ca_topic_score_gemma":0.002896482,"domain_scores_codex":[0.9976689,0.001557707,0.0001210801,0.0003428599,0.0001693083,0.0001401151],"domain_scores_gemma":[0.9929214,0.002455905,0.001976634,0.001010803,0.0004612863,0.001174075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7177193,0.00397335,0.2412337,0.0007418322,0.01291125,0.0001357202,0.0002186175,0.00142604,0.001925213,0.0002016588,0.002533601,0.01697975],"study_design_scores_gemma":[0.4006133,0.0499532,0.5222879,0.000288409,0.01846783,0.0003153489,0.0002406918,0.002799976,0.00079744,0.0007801813,0.003320611,0.000135056],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952296,0.002365716,0.0001560037,0.0002624955,0.00005680849,0.0003279964,0.001102644,0.00001669256,0.0004820739],"genre_scores_gemma":[0.9944418,0.0008595295,0.0004218675,0.0004042612,0.0001936123,0.0005428796,0.002768117,0.000009608809,0.0003583079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007579931,"threshold_uncertainty_score":0.04008704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103055004790045,"score_gpt":0.2558911846757545,"score_spread":0.2448606346278541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}