{"id":"W2587869033","doi":"10.3171/2016.9.peds16152","title":"Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma","year":2017,"lang":"en","type":"article","venue":"Journal of Neurosurgery Pediatrics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"Stichting Kinderen Kankervrij","keywords":"Medicine; Doxorubicin; Glioma; Pharmacology; Chemotherapy; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002505279,0.0002961818,0.0002393795,0.0001851159,0.00007235087,0.0001520322,0.0002512821,0.0001732707,0.0006502697],"category_scores_gemma":[0.000115688,0.0000878912,0.0001482166,0.0001500428,0.0001701923,0.0001851636,0.0001104456,0.0003841097,0.0001176741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002947396,"about_ca_system_score_gemma":0.0002956089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001204247,"about_ca_topic_score_gemma":0.001663039,"domain_scores_codex":[0.9999199,0.00001668699,0.000005176472,0.0000164929,0.00001962981,0.00002210629],"domain_scores_gemma":[0.9999398,0.00001173967,0.00001445592,0.000006192347,0.00001101735,0.00001691926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001139294,0.0007597927,0.0004318641,0.0001803967,0.00002551075,0.00008039906,0.00006858773,0.002002283,0.9837791,0.0001461594,0.0002201818,0.01116628],"study_design_scores_gemma":[0.000336119,0.03014463,0.005039953,0.00001424174,0.00007496926,0.000300762,0.0000477672,0.003909897,0.9563236,0.00003890125,0.003758186,0.00001092246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946988,0.001408705,0.002499988,0.00005533312,0.00002631374,0.0002525552,0.000330524,0.00005116452,0.0006766462],"genre_scores_gemma":[0.9955128,0.001141374,0.002278446,0.00001975205,0.000006191174,0.0001037298,0.0003347139,0.00000862051,0.0005943457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001204247,"threshold_uncertainty_score":0.002394497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04354754840933702,"score_gpt":0.3208769161206288,"score_spread":0.2773293677112918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}