{"id":"W2587878856","doi":"10.1182/blood.v126.23.2336.2336","title":"Biological Rational for the Use of Heparin in Septic Shock: Translational Data from the Halo Pilot RCT","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Thrombosis and Atherosclerosis Research Institute; McMaster University; University of Toronto","funders":"","keywords":"Medicine; Septic shock; Heparin; Sepsis; Internal medicine; Gastroenterology; Population; Surgery; Immunology; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006801792,0.0007884928,0.001772246,0.0002510886,0.000355439,0.001208565,0.0007425301,0.001292112,0.007010587],"category_scores_gemma":[0.009473491,0.0003396322,0.002676901,0.0004795751,0.001309618,0.0008298043,0.0007665667,0.001558832,0.0004802174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006049094,"about_ca_system_score_gemma":0.001793981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001016162,"about_ca_topic_score_gemma":0.001439339,"domain_scores_codex":[0.9952965,0.003871161,0.000281755,0.0001867997,0.0001702265,0.0001935029],"domain_scores_gemma":[0.9918474,0.004048616,0.002139653,0.0007769704,0.0004555234,0.0007317881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9262514,0.006950052,0.0092848,0.002453269,0.007943198,0.00008927163,0.0002063446,0.000452794,0.002884363,0.0007307313,0.001413354,0.04134037],"study_design_scores_gemma":[0.7837319,0.1710399,0.02586788,0.0009511691,0.01125652,0.00007850311,0.0003911,0.0006973657,0.001023827,0.001221363,0.003680868,0.00005958929],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729608,0.01509329,0.001343644,0.003821943,0.0006024085,0.002155706,0.0008555842,0.00004557618,0.003121068],"genre_scores_gemma":[0.9925101,0.002631132,0.001228684,0.001299663,0.0006530019,0.0008321282,0.0003735223,0.00001127388,0.0004604663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007010587,"threshold_uncertainty_score":0.03597176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6362235430599562,"score_gpt":0.3977724345873553,"score_spread":0.2384511084726009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}