{"id":"W2587952432","doi":"10.1182/blood.v106.11.63.63","title":"Adoptive Transfer of In Vitro Generated T Cell Precursors Enhances Donor T Cell Reconstitution and Graft-Versus-Tumor Activity in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Stem cell; Biology; Haematopoiesis; Bone marrow; T cell; Transplantation; Immunology; CD8; Stromal cell; Lymphopoiesis; Adoptive cell transfer; Cancer research; Molecular biology; Cell biology; Antigen; Internal medicine; Immune system; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002964722,0.0006741706,0.0003958796,0.0003974523,0.0001310959,0.0004302016,0.0003340269,0.0003237712,0.00145347],"category_scores_gemma":[0.0001775991,0.0001651059,0.000291412,0.0001540772,0.0002566896,0.0002524718,0.0002156611,0.00146213,0.0004403044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001510275,"about_ca_system_score_gemma":0.000156516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002332652,"about_ca_topic_score_gemma":0.0003898279,"domain_scores_codex":[0.9996828,0.00008726365,0.00003040543,0.00005205709,0.00006737524,0.00008016803],"domain_scores_gemma":[0.9996674,0.00006678693,0.00009293712,0.00003825038,0.00001720028,0.0001174975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003488539,0.0005321297,0.000207658,0.00004408553,0.000008512457,0.0000557448,0.00003106372,0.0001012352,0.996338,0.00008953953,0.0000726082,0.002170576],"study_design_scores_gemma":[0.00009906394,0.003997188,0.00265259,0.00001827601,0.00004884249,0.000242315,0.00002928961,0.001127731,0.9902712,0.0000376817,0.001471892,0.000003914055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962826,0.000827938,0.001150753,0.00004903231,0.00006409941,0.00006292529,0.0001912033,0.0001216941,0.001249725],"genre_scores_gemma":[0.9960107,0.0005858312,0.001172662,0.00004597438,0.00003755291,0.00005117345,0.0003505997,0.00002533644,0.001720159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00145347,"threshold_uncertainty_score":0.004862309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02139697176107776,"score_gpt":0.2620470736761161,"score_spread":0.2406501019150384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}