{"id":"W2588002066","doi":"10.1182/blood.v118.21.83.83","title":"Late Relapses Following All-Trans Retinoic Acid for Acute Promyelocytic Leukemia Are Uncommon, Respond Well to Salvage Therapy and Occur Independently of Prognostic Factors At Diagnosis: Long-Term Follow-up of North American Intergroup Study I0129","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Acute promyelocytic leukemia; Chemotherapy; Internal medicine; Anthracycline; Chemotherapy regimen; Arsenic trioxide; Surgery; Cumulative incidence; Salvage therapy; Induction chemotherapy; Randomized controlled trial; Oncology; Gastroenterology; Retinoic acid; Cohort; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001732819,0.0002422961,0.0006428148,0.0003836733,0.0005029677,0.0004764557,0.0003913697,0.00041549,0.0009871268],"category_scores_gemma":[0.001394929,0.0001708684,0.0004802597,0.0003948973,0.0002833609,0.0004170851,0.0003613966,0.0007308323,0.0002550582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002785614,"about_ca_system_score_gemma":0.0003358643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004911958,"about_ca_topic_score_gemma":0.001634807,"domain_scores_codex":[0.9993304,0.0002944976,0.00006245924,0.00007897064,0.0001311068,0.0001026065],"domain_scores_gemma":[0.9980433,0.0003437839,0.0007891682,0.000287792,0.0001438053,0.0003920442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03854863,0.001953401,0.9103166,0.0001313249,0.0004014034,0.0007757044,0.0002335298,0.0001800564,0.007466054,0.00009343833,0.001437999,0.03846191],"study_design_scores_gemma":[0.001479372,0.01072333,0.9830225,0.00002580175,0.0002043304,0.001028455,0.000111407,0.0002196644,0.001266009,0.0001023479,0.001802037,0.00001471517],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979721,0.0007379965,0.0001629521,0.00005412917,0.000009777751,0.0000880168,0.0003954129,0.00001091332,0.0005688217],"genre_scores_gemma":[0.997283,0.0002276181,0.0001353837,0.000117536,0.00002967363,0.0001319687,0.001367854,0.000003748149,0.0007031783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001732819,"threshold_uncertainty_score":0.009164155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02131233401937273,"score_gpt":0.2624086929589308,"score_spread":0.241096358939558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}