{"id":"W2588054188","doi":"10.1093/ndt/gfw153.02","title":"SO050LONG-TERM FOLLOW-UP STUDY OF ECULIZUMAB FOR PREVENTION OF THROMBOTIC MICROANGIOPATHY IN PATIENTS WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME","year":2016,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"IgG4-Related and Inflammatory Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Thrombotic microangiopathy; Eculizumab; Medicine; Atypical hemolytic uremic syndrome; Internal medicine; Microangiopathy; Gastroenterology; Immunology; Complement system; Endocrinology; Diabetes mellitus; Antibody; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001305617,0.0003495564,0.0007810471,0.0002188756,0.0003911438,0.0004778047,0.0002680575,0.000475335,0.0011709],"category_scores_gemma":[0.001168563,0.0001784392,0.0006689646,0.0002561041,0.0001746097,0.0003336733,0.0002833207,0.0007375287,0.0001837951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002864474,"about_ca_system_score_gemma":0.0004081933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005929309,"about_ca_topic_score_gemma":0.001147255,"domain_scores_codex":[0.9994457,0.0002494137,0.00005996436,0.00008010065,0.00009968402,0.00006511976],"domain_scores_gemma":[0.9988264,0.0001765063,0.0003993844,0.00007450021,0.0001300699,0.0003931724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2053541,0.008542909,0.7129114,0.00035782,0.002208114,0.000295602,0.0002225065,0.0003009902,0.007792098,0.00008176546,0.001080911,0.06085176],"study_design_scores_gemma":[0.02200863,0.08275024,0.8899491,0.00008179975,0.001261053,0.0003312802,0.00006836418,0.0007046279,0.001086472,0.00005426501,0.001685557,0.00001861408],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983019,0.0009393044,0.00006558439,0.00005454556,0.00001666707,0.00007216175,0.0001669311,0.000003430407,0.0003794691],"genre_scores_gemma":[0.9984908,0.0002903686,0.0001531868,0.0001380811,0.00004363793,0.00009129433,0.0005276455,0.000001036822,0.0002639362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001305617,"threshold_uncertainty_score":0.006904781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008353236537926672,"score_gpt":0.2376371744616412,"score_spread":0.2292839379237145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}