{"id":"W2588347050","doi":"10.1182/blood.v106.11.1558.1558","title":"Single Nucleotide Polymorphisms (SNPs) and Recurrent Mutations in the Hyaluronan Synthase 1 (HAS1) Gene May Predispose to Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Exon; Biology; RNA splicing; Single-nucleotide polymorphism; Intron; Exonic splicing enhancer; Molecular biology; Gene; Polypyrimidine tract; Genetics; Cancer research; Alternative splicing; Genotype; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001995452,0.0001967722,0.0001439007,0.00008231753,0.0001147496,0.00007614439,0.0002271302,0.0001079471,0.0000172052],"category_scores_gemma":[0.0001868083,0.0001671827,0.00004392997,0.0001365236,0.0001310771,0.000009984913,0.0002076001,0.0001521166,0.00001553357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001837824,"about_ca_system_score_gemma":0.00004675275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006027529,"about_ca_topic_score_gemma":0.0005480284,"domain_scores_codex":[0.998576,0.0001109884,0.0002404586,0.000466178,0.0002102185,0.0003961894],"domain_scores_gemma":[0.9993083,0.00005915261,0.00004615966,0.0003604445,0.00004503331,0.0001809215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001324801,0.0005494842,0.01578792,0.00002211125,0.00003748936,0.00003122984,0.0004006812,0.0000201914,0.9614884,0.00001306005,0.0005141225,0.02100283],"study_design_scores_gemma":[0.003522175,0.001759109,0.1255785,0.0000692678,0.00006678513,0.0002917229,0.0002658859,0.0002832208,0.8505509,0.00002294437,0.01711782,0.0004716813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969028,0.0009132663,0.00004155659,0.001286473,0.00004157279,0.0004909324,0.0001661708,0.00001468259,0.0001424963],"genre_scores_gemma":[0.995916,0.00004483791,0.003292091,0.0002061022,0.0002314155,0.00005909966,0.0001083559,0.00003005277,0.0001120557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1109375,"threshold_uncertainty_score":0.6817513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01270167125010874,"score_gpt":0.2547918201655684,"score_spread":0.2420901489154597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}