{"id":"W2588439324","doi":"10.1093/annonc/mdw365.04","title":"Impact of palbociclib plus letrozole on health related quality of life (HRQOL) compared with letrozole alone in treatment naïve postmenopausal patients with ER+ HER2- metastatic breast cancer (MBC): results from PALOMA-2","year":2016,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Letrozole; Palbociclib; Medicine; Quality of life (healthcare); Metastatic breast cancer; Breast cancer; Internal medicine; Placebo; Oncology; Cancer; Tamoxifen; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004801878,0.0004857256,0.001160979,0.000248748,0.0001674521,0.0004902862,0.0003638283,0.0004565219,0.002351688],"category_scores_gemma":[0.0007785829,0.000192534,0.00149959,0.0002966427,0.0002701897,0.0004537976,0.0002401833,0.001207583,0.0002982318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006051579,"about_ca_system_score_gemma":0.0006339551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002223611,"about_ca_topic_score_gemma":0.00662219,"domain_scores_codex":[0.9997784,0.00008345369,0.00001638085,0.00003918688,0.00003064538,0.00005197893],"domain_scores_gemma":[0.9997101,0.0000948317,0.00006500938,0.00001791752,0.00001634218,0.00009579886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8625276,0.01069905,0.02058164,0.0004889506,0.002919727,0.0001217216,0.0001185355,0.001125916,0.006814839,0.00007736249,0.00101653,0.09350818],"study_design_scores_gemma":[0.2810631,0.4745311,0.2269237,0.0001210219,0.008868775,0.0002727237,0.0003152749,0.002138279,0.003014179,0.0002687709,0.002415685,0.00006733604],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973733,0.001443449,0.00002514655,0.0001599613,0.0000288434,0.0000563288,0.0003647312,0.000009288135,0.0005388538],"genre_scores_gemma":[0.9972843,0.001021625,0.0001206845,0.000189348,0.00005381637,0.00009396839,0.0005533904,0.000003769066,0.0006791285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002351688,"threshold_uncertainty_score":0.007867217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08483000578050044,"score_gpt":0.411805459225645,"score_spread":0.3269754534451446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}