{"id":"W2588543544","doi":"10.1093/neuonc/now212.611","title":"PDCT-07. HERBY (BO25041): A PHASE II OPEN-LABEL, RANDOMIZED, MULTICENTER, COMPARATIVE STUDY OF BEVACIZUMAB (BEV)-BASED THERAPY IN PEDIATRIC PATIENTS WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMA (HGG)","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Temozolomide; Bevacizumab; Internal medicine; Hazard ratio; Glioma; Clinical endpoint; Oncology; Confidence interval; Radiation therapy; Surgery; Randomized controlled trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00109824,0.001022521,0.00138434,0.0003766562,0.0003069236,0.0006457545,0.000708937,0.0009172899,0.003790456],"category_scores_gemma":[0.000631923,0.0005178055,0.0007542141,0.0004648456,0.0006752181,0.0006645297,0.0002542887,0.00186831,0.0006552225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009365553,"about_ca_system_score_gemma":0.001832251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001546633,"about_ca_topic_score_gemma":0.006102647,"domain_scores_codex":[0.9997323,0.0001193585,0.00001490269,0.00005253568,0.00003090582,0.00005006602],"domain_scores_gemma":[0.9995843,0.00005417748,0.0001106361,0.00002434608,0.00003212001,0.0001945054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8410178,0.04654346,0.006845352,0.001258422,0.001877172,0.0001757756,0.0001861715,0.00144543,0.0259409,0.0004960024,0.005224212,0.06898928],"study_design_scores_gemma":[0.7590102,0.2242975,0.01034327,0.00003687144,0.0006008723,0.0002297314,0.00004593792,0.000840426,0.001800364,0.0001531804,0.002617849,0.00002380502],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989243,0.002262317,0.0005627724,0.0002835706,0.0001229663,0.004089498,0.001600902,0.00009498931,0.001739846],"genre_scores_gemma":[0.9850096,0.00244665,0.002415856,0.0009376442,0.0001598433,0.004355947,0.002556908,0.00002563084,0.002091989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003790456,"threshold_uncertainty_score":0.01268035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03779860040226422,"score_gpt":0.3425924890538058,"score_spread":0.3047938886515416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}