{"id":"W2588570873","doi":"10.1016/j.ejca.2017.08.019","title":"Efficacy and safety of subcutaneous trastuzumab and intravenous trastuzumab as part of adjuvant therapy for HER2-positive early breast cancer: Final analysis of the randomised, two-cohort PrefHer study","year":2017,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Universitätsklinikum Hamburg-Eppendorf; Centre Léon Bérard; Assistance publique-Hôpitaux de Paris; Baskent Üniversitesi; Gaziantep Üniversitesi; Ege Üniversitesi; Institut Bergonié; University of Sussex; F. Hoffmann-La Roche; Roche","keywords":"Trastuzumab; Medicine; Breast cancer; Adjuvant; Oncology; Internal medicine; Adjuvant therapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006237868,0.001948288,0.004278198,0.0004762477,0.0003727144,0.001465492,0.001423114,0.002311176,0.003167088],"category_scores_gemma":[0.006369546,0.001128378,0.004008585,0.0005871631,0.002303625,0.001966056,0.000800423,0.003275786,0.0007002415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001319876,"about_ca_system_score_gemma":0.001373354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093359,"about_ca_topic_score_gemma":0.001174842,"domain_scores_codex":[0.9951134,0.003204224,0.0002426336,0.0005756522,0.000338812,0.0005253677],"domain_scores_gemma":[0.994979,0.00226203,0.0008605705,0.0009486393,0.000233526,0.0007163444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9882985,0.0022512,0.001344094,0.00009443674,0.0008864741,0.00001890331,0.00003789679,0.0002824239,0.001275956,0.00003823406,0.00009472683,0.005377145],"study_design_scores_gemma":[0.7838093,0.191481,0.01880843,0.00003383883,0.003016016,0.00006263779,0.00005473623,0.0008397765,0.001130989,0.0002688803,0.0004386868,0.00005582134],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970203,0.001338082,0.0003298613,0.0001146362,0.0001097601,0.000275748,0.0003541022,0.00002453441,0.0004329794],"genre_scores_gemma":[0.9970486,0.0005818603,0.0003459449,0.00014923,0.0001741558,0.000257247,0.0006667092,0.00001914232,0.0007572218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006237868,"threshold_uncertainty_score":0.03298938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0284409973456826,"score_gpt":0.3521403557355309,"score_spread":0.3236993583898483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}