{"id":"W2588612665","doi":"10.1126/scitranslmed.aag1809","title":"Delayed differentiation of potent effector CD8 <sup>+</sup> T cells reducing viremia and reservoir seeding in acute HIV infection","year":2017,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; U.S. Department of Defense","keywords":"Viremia; Effector; Virology; CD8; Immunology; Cytotoxic T cell; Seeding; Biology; Human immunodeficiency virus (HIV); Medicine; Immune system; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000252829,0.000236394,0.0002434823,0.0001449087,0.000119656,0.0003854138,0.0001745843,0.000323662,0.001761488],"category_scores_gemma":[0.0002888718,0.0001106129,0.0001152088,0.00007765042,0.0002792381,0.0002524944,0.0002187322,0.000954012,0.0003914481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001115725,"about_ca_system_score_gemma":0.0001658018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008521078,"about_ca_topic_score_gemma":0.0001824254,"domain_scores_codex":[0.9999142,0.00002244906,0.00001000612,0.000008985264,0.00001462911,0.00002976321],"domain_scores_gemma":[0.9998972,0.00002327669,0.00001802323,0.00001126118,0.00001196686,0.00003825812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001200539,0.0004655166,0.00147551,0.0001461652,0.000005786785,0.0001797331,0.00007136766,0.0005098759,0.9632446,0.0006828647,0.000300783,0.03171726],"study_design_scores_gemma":[0.0004090725,0.005801005,0.01428189,0.00006056742,0.0000387262,0.001121788,0.0001530634,0.002303432,0.9678777,0.001231549,0.006710846,0.00001028787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943389,0.00175879,0.00228481,0.0002060772,0.00005205103,0.00004766696,0.00005207332,0.00006201205,0.001197564],"genre_scores_gemma":[0.9945996,0.0008838683,0.002471548,0.0001212213,0.00004560231,0.00003920468,0.00008755839,0.00001937863,0.001732049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001761488,"threshold_uncertainty_score":0.005892813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01998848963645957,"score_gpt":0.3009737281956563,"score_spread":0.2809852385591967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}