{"id":"W2588666144","doi":"10.1093/neuonc/now212.184","title":"CSIG-23. CYTOPLASMIC RNA STRESS GRANULES: A PUTATIVE TRANSLATIONAL MECHANISM OF mTOR REGULATION IN GLIOBLASTOMA","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Dalhousie University","funders":"","keywords":"Stress granule; PI3K/AKT/mTOR pathway; Messenger RNA; P-bodies; RNA-binding protein; Cell biology; Molecular biology; Protein biosynthesis; RNA; Translation (biology); Biology; Chemistry; Signal transduction; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007871784,0.0002849797,0.0002864952,0.0003870521,0.0002326314,0.0003715379,0.0001645933,0.0002345718,0.001158613],"category_scores_gemma":[0.00007344622,0.0001331074,0.0003002806,0.0003047365,0.0001628272,0.0001033342,0.0001455688,0.0002657581,0.0005092834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000446957,"about_ca_system_score_gemma":0.0002620766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593136,"about_ca_topic_score_gemma":0.003021278,"domain_scores_codex":[0.999908,0.000007126632,0.000007553817,0.00002584003,0.00002533388,0.0000262073],"domain_scores_gemma":[0.999949,0.000003727963,0.00001684776,0.000004317264,0.000007877044,0.0000183071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001414065,0.000009712545,0.0007944119,0.00004720617,0.000007063675,0.00008264832,0.00001148667,0.0000295651,0.9975551,0.00004816588,0.0001156657,0.001157632],"study_design_scores_gemma":[0.00002896023,0.0004554886,0.1331606,0.00001958781,0.00005990698,0.000686498,0.00009843458,0.001377384,0.8568637,0.0001454433,0.007089551,0.00001441044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885138,0.003483321,0.001941264,0.0002185205,0.00004439039,0.00005437315,0.003569973,0.0002166391,0.001957676],"genre_scores_gemma":[0.9871357,0.001202647,0.002737186,0.0001991376,0.00002178631,0.00008909304,0.005238934,0.00004712871,0.003328435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593136,"threshold_uncertainty_score":0.003875971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078041231991258,"score_gpt":0.245153380944256,"score_spread":0.2343729686243434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}