{"id":"W2588672442","doi":"10.1182/blood-2016-08-737239","title":"IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Medical Research Council; Institut National Du Cancer; Versus Arthritis; National Centre for the Replacement, Refinement and Reduction of Animals in Research; Michael Smith Health Research BC","keywords":"Stromal cell; Germinal center; Cancer research; Biology; Bone marrow; Follicular lymphoma; Stroma; Tumor microenvironment; Follicular dendritic cells; CXCL13; Mantle zone; B cell; Cell biology; Lymphoma; Immunology; Chemokine; T cell; Immune system; Chemokine receptor; Antigen-presenting cell; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358354,0.000246039,0.0001822607,0.0003461229,0.0002199255,0.0003454094,0.0001026763,0.0001879167,0.002750417],"category_scores_gemma":[0.00011998,0.00009255395,0.0001527892,0.0001400695,0.0002228075,0.000164301,0.0002062879,0.000504962,0.0003796617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004539391,"about_ca_system_score_gemma":0.0003544198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009627701,"about_ca_topic_score_gemma":0.001192035,"domain_scores_codex":[0.9998249,0.00004061769,0.00001228555,0.00002469277,0.0000385233,0.00005905884],"domain_scores_gemma":[0.9999163,0.0000106833,0.00002142203,0.000007853099,0.0000150776,0.00002862164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002165241,0.00003056216,0.001189292,0.000042827,0.000004297947,0.0001179871,0.00002907362,0.0000822966,0.9923669,0.0001804682,0.0001571417,0.005582766],"study_design_scores_gemma":[0.00007125303,0.0006726168,0.02739682,0.00001701483,0.00003532458,0.001286718,0.0001400292,0.001550826,0.9563342,0.0002221657,0.01226383,0.000009105977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897225,0.003053681,0.00269201,0.000299951,0.00003279727,0.00004819057,0.0005392475,0.00026148,0.003350146],"genre_scores_gemma":[0.9958332,0.0003398771,0.001083684,0.00003039495,0.0000125204,0.00003262215,0.0003212048,0.00001183086,0.002334703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002750417,"threshold_uncertainty_score":0.009201109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01429776879337591,"score_gpt":0.2490686414985862,"score_spread":0.2347708727052103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}