{"id":"W2588679592","doi":"10.1038/srep42542","title":"Structural and functional characterization of deep-sea thermophilic bacteriophage GVE2 HNH endonuclease","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Beijing Synchrotron Radiation Facility; State Key Laboratory of Virology; Yangzhou University; Government of Jiangsu Province; National Natural Science Foundation of China; University of Alberta","keywords":"Endonuclease; Bacteriophage; Mutant; Thermophile; DNA; Enzyme; Biology; Biochemistry; Wild type; Molecular biology; Chemistry; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000217759,0.0003433653,0.0002839935,0.0002126401,0.0001276681,0.0002740361,0.0002118926,0.0003288657,0.0005192165],"category_scores_gemma":[0.0003292123,0.0001456177,0.0003524349,0.0002896089,0.0001664912,0.0001676302,0.0002042808,0.0003447791,0.0002467414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002515599,"about_ca_system_score_gemma":0.0001987189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002047099,"about_ca_topic_score_gemma":0.001556765,"domain_scores_codex":[0.9998556,0.00002231845,0.00001533299,0.00002912691,0.00005308866,0.00002446819],"domain_scores_gemma":[0.9997554,0.00003766111,0.00005642372,0.00002588911,0.00006241351,0.0000621901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007376816,0.00002726992,0.001057029,0.00003304926,0.000007090132,0.00006294585,0.00003562653,0.0001351333,0.9978388,0.00003253577,0.00001935517,0.0006774136],"study_design_scores_gemma":[0.00001520143,0.0002413775,0.03525795,0.000006697101,0.00002309532,0.0005290441,0.0001147632,0.001950012,0.9596016,0.0000495986,0.002196296,0.00001432121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976742,0.0004027438,0.00108529,0.00003341438,0.000007347219,0.00001166702,0.0004613924,0.0000143026,0.0003096177],"genre_scores_gemma":[0.9931843,0.0002462612,0.002374675,0.00003277089,0.00000552938,0.00001312321,0.002854332,0.00001999574,0.001269067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002047099,"threshold_uncertainty_score":0.004070401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139623621807647,"score_gpt":0.2201350653577414,"score_spread":0.2087388291396649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}